ID B8NF85_ASPFN Unreviewed; 247 AA.
AC B8NF85;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Dihydroflavonal-4-reductase, putative {ECO:0000313|EMBL:EED51866.1};
GN ORFNames=AFLA_061290 {ECO:0000313|EMBL:EED51866.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED51866.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED51866.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; EQ963477; EED51866.1; -; Genomic_DNA.
DR RefSeq; XP_002378873.1; XM_002378832.1.
DR AlphaFoldDB; B8NF85; -.
DR STRING; 332952.B8NF85; -.
DR EnsemblFungi; EED51866; EED51866; AFLA_061290.
DR VEuPathDB; FungiDB:AFLA_005181; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_9_2_1; -.
DR OMA; FDYIIHT; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 6..206
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 247 AA; 27367 MW; 315F83EC6EA7F64B CRC64;
MQAKWPGKLT LFEADLLKPG SFDEPAKGCS VVYHIASPFF IESRIRDGQK EVVEPALKGT
QHVLDAVQKC ETIKLVVVTS SVAAIFGDNA DVQSMKDNTL SSEYFNTTST VTHNSYSYSK
VIAEKEAWKY YEAQPSPQRW RLVTINPGLV LGPSLSPTSE SGSLSLLDQL LRGELFLGVP
DLWFATVDVR EVATAHLRVA QNPDSHGRYI LADKETHSFV EFARILRSLA HSSRIPEHKL
PNSLVIA
//
