ID B8NF89_ASPFN Unreviewed; 442 AA.
AC B8NF89;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Inositol 5-phosphatase, putative {ECO:0000313|EMBL:EED51870.1};
GN ORFNames=AFLA_061330 {ECO:0000313|EMBL:EED51870.1}, G4B84_007650
GN {ECO:0000313|EMBL:QMW32219.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED51870.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED51870.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED51870.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW32219.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW32219.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; EQ963477; EED51870.1; -; Genomic_DNA.
DR EMBL; CP059870; QMW32219.1; -; Genomic_DNA.
DR RefSeq; XP_002378877.1; XM_002378836.1.
DR AlphaFoldDB; B8NF89; -.
DR STRING; 332952.B8NF89; -.
DR EnsemblFungi; EED51870; EED51870; AFLA_061330.
DR VEuPathDB; FungiDB:AFLA_005185; -.
DR eggNOG; KOG0565; Eukaryota.
DR HOGENOM; CLU_025224_1_1_1; -.
DR OMA; FNCARNP; -.
DR OrthoDB; 1329119at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProt.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR PANTHER; PTHR11200:SF286; 5-PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07600)-RELATED; 1.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 404..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..376
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
FT REGION 188..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 49069 MW; 047048C93FB9DEF6 CRC64;
MESLTLYMLT FNCARNPVDV DRFAHHFFDA LPLTDSSSAP TPPDLIVLSL QEIAPIAYAF
LGGSFLAPYF ASLSQVVERA VSNRWETHYV NMVTDNSGMT GLMVYARSDV AERISSIDTT
RVGFGFQQMG NKGAVGARLA YATQNTLDDT VDLTFIAAHL APMEYAVRQR NEDWRSMVER
LVFDRATPRA RENAETGDDS ESTALLNSST RSSGDDYRGI FIPTSYLFLA GDLNYRTSDA
SPRSEDCARF PQAEVDPADP RHFSHLLKED QLTREMRQSR SFHGLSEAPI TFPPTYKYTN
AARQAAARGT GSEEWLWTST RWPSWCDRVL YLETLPGLGE EARVRPLKYN SLPLFPTSDH
RAVALSASVP VSSRPPADAT QSAIPFRIDP EWASKRDAAR RKELVVGCLA YLGLTWEGNG
LLVASVIGVL GAWLVLRSLF NA
//
