ID B8P9F6_POSPM Unreviewed; 1147 AA.
AC B8P9F6;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=POSPLDRAFT_106733 {ECO:0000313|EMBL:EED82492.1};
OS Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus)
OS (Poria monticola).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Postiaceae; Postia.
OX NCBI_TaxID=561896 {ECO:0000313|Proteomes:UP000001743};
RN [1] {ECO:0000313|EMBL:EED82492.1, ECO:0000313|Proteomes:UP000001743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 44394 / Madison 698-R {ECO:0000313|Proteomes:UP000001743};
RX PubMed=19193860; DOI=10.1073/pnas.0809575106;
RA Martinez D., Challacombe J., Morgenstern I., Hibbett D., Schmoll M.,
RA Kubicek C.P., Ferreira P., Ruiz-Duenas F.J., Martinez A.T., Kersten P.,
RA Hammel K.E., Vanden Wymelenberg A., Gaskell J., Lindquist E., Sabat G.,
RA Splinter BonDurant S., Larrondo L.F., Canessa P., Vicuna R., Yadav J.,
RA Doddapaneni H., Subramanian V., Pisabarro A.G., Lavin J.L., Oguiza J.A.,
RA Master E., Henrissat B., Coutinho P.M., Harris P., Magnuson J.K.,
RA Baker S.E., Bruno K., Kenealy W., Hoegger P.J., Kuees U., Ramaiya P.,
RA Lucas S., Salamov A., Shapiro H., Tu H., Chee C.L., Misra M., Xie G.,
RA Teter S., Yaver D., James T., Mokrejs M., Pospisek M., Grigoriev I.V.,
RA Brettin T., Rokhsar D., Berka R., Cullen D.;
RT "Genome, transcriptome, and secretome analysis of wood decay fungus Postia
RT placenta supports unique mechanisms of lignocellulose conversion.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:1954-1959(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; EQ966286; EED82492.1; -; Genomic_DNA.
DR RefSeq; XP_002472324.1; XM_002472279.1.
DR AlphaFoldDB; B8P9F6; -.
DR STRING; 561896.B8P9F6; -.
DR KEGG; ppl:POSPLDRAFT_106733; -.
DR HOGENOM; CLU_008262_0_0_1; -.
DR InParanoid; B8P9F6; -.
DR OMA; KINDAEC; -.
DR OrthoDB; 317994at2759; -.
DR Proteomes; UP000001743; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.490; -; 2.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 3.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR031303; C5_meth_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF00145; DNA_methylase; 2.
DR SMART; SM00439; BAH; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51038; BAH; 2.
DR PROSITE; PS00095; C5_MTASE_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001743};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 376..501
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 527..668
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT REGION 85..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..602
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1147 AA; 130146 MW; 5093B88357BD1E6A CRC64;
MSRSLAHRPR YEIPEDEQIE DDLVVDGETV ADPQDDETIP IRVLDDFAIY EWFGLHMVGI
AELLGLTPES EDGITYGASG IVRSYTDSSD NEDDGDDGSE TSAVPSLQPR VKLSQIIEFN
VHNVSCKRGR DLQIDPLPVH VLKKDMVSNI YIRTQNSWYI LDQPLDSYYP FFIDFWIKHR
LLHLTISSSL ADPTTTTDQF VELLAVTPES SDEVGIALKF LSRELGEQDL NADDTRAYIE
SMIQMLCADD PQLRRALSHV PLICSLVELN VSSQSGKKES ATHKERIKKT FKDIEKNVLL
HRERTIVTPT VARIAGDLFV QTLKVTGESL EEKASDDNGM EFDVAPVHYT DPARIEWVPT
SRIAPYYYKS VIVDGVKYSA CYLTFVNYMI QNANFQFCQI AYMFERQETL KCKYGSKPVT
RKYFHARWLQ HGSQMLLQET AHPNGLFYLN ECDDLPVECI YRRCNLRVLG PDEPEPIEEP
SDLFFARMIW DSTQAALVNV TDQDIQAAIG QATWTPCSDG GISRFGIDYH VHDFVYVMPH
SSSPNAALFE IGQLVNLILD ADSHVLEVEV RWYKRYDLVV QKCPDDDDDD DDDDDDDDDD
TSSRVVSDNR RLYRTREYET INADRIQGKA YVAFIESRDR RDEWLQHDDH FYTDLYTNNS
IAQSLDDLHT LTKSIPQCLV CRQQRIDQLE SEVEVLDRKG PLRGLELFAG LELSGFVQTK
WAVEFSPGAA LTFQENHTNA IVYNQDSNVL LKHALAAHEG NNPEPLLSLR EDERHELPPM
PTQGEVDFIY GGRQVGRAIV GGIKMGVVKF IIRALVCLGY QVHFKVVDAG HYGAAQSRRR
VIFWGAKQGV PLPKFPKPMH DLTKRSFHSF KLPTGEVLKP VTWSIRHKES GQSNHQCVPL
LPVTVNDAIA DLPSFDWVNP FNEIRPGPKD LDEIGLRLAK GIRRFDAVPS LEPRLAGFTD
PVPYAHPPMS RYQLWIRQGA GAEVTHHYTR LFPARIVERV VRVPLTPNAN HEGLPAKLRV
GRLFESSGDA RKRYDRVYGR IDGDQIFQTA LTTVAPNSKV GRVLHPNQKR ILTVRECARA
QGFPDKYEFH SVNTKLSDRV ADQHRQIGNA VPVPLGLALG KELGKALMLY WDQQDVNVSE
RSLSPEV
//
