ID B8PLR5_POSPM Unreviewed; 535 AA.
AC B8PLR5;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=POSPLDRAFT_91963 {ECO:0000313|EMBL:EED78189.1};
OS Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus)
OS (Poria monticola).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Postiaceae; Postia.
OX NCBI_TaxID=561896 {ECO:0000313|Proteomes:UP000001743};
RN [1] {ECO:0000313|EMBL:EED78189.1, ECO:0000313|Proteomes:UP000001743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 44394 / Madison 698-R {ECO:0000313|Proteomes:UP000001743};
RX PubMed=19193860; DOI=10.1073/pnas.0809575106;
RA Martinez D., Challacombe J., Morgenstern I., Hibbett D., Schmoll M.,
RA Kubicek C.P., Ferreira P., Ruiz-Duenas F.J., Martinez A.T., Kersten P.,
RA Hammel K.E., Vanden Wymelenberg A., Gaskell J., Lindquist E., Sabat G.,
RA Splinter BonDurant S., Larrondo L.F., Canessa P., Vicuna R., Yadav J.,
RA Doddapaneni H., Subramanian V., Pisabarro A.G., Lavin J.L., Oguiza J.A.,
RA Master E., Henrissat B., Coutinho P.M., Harris P., Magnuson J.K.,
RA Baker S.E., Bruno K., Kenealy W., Hoegger P.J., Kuees U., Ramaiya P.,
RA Lucas S., Salamov A., Shapiro H., Tu H., Chee C.L., Misra M., Xie G.,
RA Teter S., Yaver D., James T., Mokrejs M., Pospisek M., Grigoriev I.V.,
RA Brettin T., Rokhsar D., Berka R., Cullen D.;
RT "Genome, transcriptome, and secretome analysis of wood decay fungus Postia
RT placenta supports unique mechanisms of lignocellulose conversion.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:1954-1959(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-
CC O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+);
CC Xref=Rhea:RHEA:67452, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30879, ChEBI:CHEBI:171667, ChEBI:CHEBI:171668;
CC EC=3.1.1.117; Evidence={ECO:0000256|ARBA:ARBA00024511};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:67453;
CC Evidence={ECO:0000256|ARBA:ARBA00024511};
CC -!- SIMILARITY: Belongs to the carbohydrate esterase 15 (CE15) family.
CC {ECO:0000256|ARBA:ARBA00010092}.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; EQ966464; EED78189.1; -; Genomic_DNA.
DR RefSeq; XP_002476624.1; XM_002476579.1.
DR AlphaFoldDB; B8PLR5; -.
DR ESTHER; pospm-b8plr5; Fungal_carboxylesterase_lipase.
DR KEGG; ppl:POSPLDRAFT_91963; -.
DR HOGENOM; CLU_006586_10_7_1; -.
DR InParanoid; B8PLR5; -.
DR OMA; FGEDCLC; -.
DR OrthoDB; 1463590at2759; -.
DR Proteomes; UP000001743; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000001743};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 22..535
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005124138"
FT DOMAIN 36..493
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 535 AA; 58019 MW; 9265AC82099FB1AD CRC64;
MFSYCLLASI CFAYIAHGVH ALPSYSNNAS GPSGPMVDVG YAAFLGNDSI PGFPGIEFFG
GIRYVQPPLG ELRFRAPQRL DETVGPHNVT DARDWGDICM QEPAQVGFGS EDCLTLNVWR
SAGTQAGDNV PVALYIHSAQ GFPMSSWVNE TGGAMMGVNI QYRLGMFGFL ASAAVQEDGD
MNAGLLDQRA AFDWVRRHIS RFGGDPGRIT VSGQSAGSAD IVHQMVSYGG QGEPPFQAAI
AQSIGMDPLP IAEEYESIMG CLRAAPLSAL VTAINSRPSS CGFLPVVDGT ILPALPSQLI
ATGRFHRMPF VGGHVTDDGS IFVGDPANFV NTTDGFVASI MKRYTLLSNT TIARMIELYP
LSDFPSQWER AKRAFGDTVF TCIQLAFDRD WIIAQKLMSE GRTDAYNYRF NTPDPVQLAA
NPWEGCVVVR VPSVCSPRLM GVHVVQGQTL FAPFNASEKV LATETIGYWT SFSRAFSPNT
FKPLGSSPEW LTADSGRLVI EEGGVNGTGS YMEERSQAYE ERCAFWMEVG TETRV
//
