ID B8PML2_POSPM Unreviewed; 806 AA.
AC B8PML2;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Glycoside hydrolase family 5 protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=POSPLDRAFT_134779 {ECO:0000313|EMBL:EED77883.1};
OS Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus)
OS (Poria monticola).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Postiaceae; Postia.
OX NCBI_TaxID=561896 {ECO:0000313|Proteomes:UP000001743};
RN [1] {ECO:0000313|EMBL:EED77883.1, ECO:0000313|Proteomes:UP000001743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 44394 / Madison 698-R {ECO:0000313|Proteomes:UP000001743};
RX PubMed=19193860; DOI=10.1073/pnas.0809575106;
RA Martinez D., Challacombe J., Morgenstern I., Hibbett D., Schmoll M.,
RA Kubicek C.P., Ferreira P., Ruiz-Duenas F.J., Martinez A.T., Kersten P.,
RA Hammel K.E., Vanden Wymelenberg A., Gaskell J., Lindquist E., Sabat G.,
RA Splinter BonDurant S., Larrondo L.F., Canessa P., Vicuna R., Yadav J.,
RA Doddapaneni H., Subramanian V., Pisabarro A.G., Lavin J.L., Oguiza J.A.,
RA Master E., Henrissat B., Coutinho P.M., Harris P., Magnuson J.K.,
RA Baker S.E., Bruno K., Kenealy W., Hoegger P.J., Kuees U., Ramaiya P.,
RA Lucas S., Salamov A., Shapiro H., Tu H., Chee C.L., Misra M., Xie G.,
RA Teter S., Yaver D., James T., Mokrejs M., Pospisek M., Grigoriev I.V.,
RA Brettin T., Rokhsar D., Berka R., Cullen D.;
RT "Genome, transcriptome, and secretome analysis of wood decay fungus Postia
RT placenta supports unique mechanisms of lignocellulose conversion.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:1954-1959(2009).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641}.
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DR EMBL; EQ966506; EED77883.1; -; Genomic_DNA.
DR RefSeq; XP_002476919.1; XM_002476874.1.
DR AlphaFoldDB; B8PML2; -.
DR KEGG; ppl:POSPLDRAFT_134779; -.
DR HOGENOM; CLU_009024_1_0_1; -.
DR InParanoid; B8PML2; -.
DR OMA; NEFIPPW; -.
DR OrthoDB; 69117at2759; -.
DR Proteomes; UP000001743; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF1; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001743};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 782..802
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 131..325
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 655..763
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
SQ SEQUENCE 806 AA; 90205 MW; 44E9B0BAEA65F61A CRC64;
MISRTASDAS FIFVRQDQDA SQDLAASRLT ESELLVDKSN VETPRAEVDR ALAQPQSPAA
RPPAPKAAPS FAHDWSAAGT GGRLYTHGRH FVDAYGRVCN LRGVNLAGNC KTPTNHDHDT
FPANHADVTF VGRPFPLEEA HEHFARLRRW GLTFIRFLVT WEAVEHAGPG IYDTEYLAYL
RSILSLLPQF GLTAFVALHQ DVWSRYTGGS GAPAWTLEAV GFDLHGLEEP GAAWLRGVRG
GGHTEDERGL WPCGYQKLSA ATMATCFWAG DAFAPKLRVR DARGADVSIQ TFLQTAFLDM
WEVVAKTVGD LEGVLGFEIM NEPHRGYAEL QSMHQFDYNT DLHLGHVPTA FQSFTLGAGY
PTEVGFWTRT FPMPTRLTGK AVLNTARQKA WRQDGPTGGR CLWEMHGVWG WDLKKNEGVV
LRESYFKKHP MTGKTIDWYT DFFYPFVQRW AERVRSVSSP DKLVLVEPIP NEFCPSSWTP
ERQPPNVVYA PHWYDLNALF TKAFGDFTAN VQGLSRGMFI LKALYWGHQG ARENFSLQIR
NIVEAGYRSL GERPVVIGEC GIPMDMNKGE AFQTDSWIWQ TRMMDAMLTA LDKSLVGFTL
WNYNPDNEDH IGDDWNGENF SWFSRRRALT GDWLDLAQTS PTLDNGARIV RAFVRPYPAK
TAGIPVRFDY EMNTGQFTFE WVIPGVDSAP PAEASVASPP LASHPALTSK DTQIFLPSLL
AHSRKIVVQG LKPEDRYRYD EARQTLTITT ADLVPGERHS VTVSLNPPLK DAFTVNSFWD
DFGLHVVAAT IVLASILIYV IMSMVS
//
