ID B9EC39_MACCJ Unreviewed; 372 AA.
AC B9EC39;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN OrderedLocusNames=MCCL_1093 {ECO:0000313|EMBL:BAH17800.1};
OS Macrococcus caseolyticus (strain JCSC5402).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Macrococcus.
OX NCBI_TaxID=458233 {ECO:0000313|EMBL:BAH17800.1, ECO:0000313|Proteomes:UP000001383};
RN [1] {ECO:0000313|EMBL:BAH17800.1, ECO:0000313|Proteomes:UP000001383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCSC5402 {ECO:0000313|EMBL:BAH17800.1,
RC ECO:0000313|Proteomes:UP000001383};
RX PubMed=19074389; DOI=10.1128/JB.01058-08;
RA Baba T., Kuwahara-Arai K., Uchiyama I., Takeuchi F., Ito T., Hiramatsu K.;
RT "Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402,
RT reflecting the ancestral genome of the human-pathogenic staphylococci.";
RL J. Bacteriol. 191:1180-1190(2009).
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DR EMBL; AP009484; BAH17800.1; -; Genomic_DNA.
DR RefSeq; WP_012656998.1; NC_011999.1.
DR AlphaFoldDB; B9EC39; -.
DR STRING; 458233.MCCL_1093; -.
DR KEGG; mcl:MCCL_1093; -.
DR eggNOG; COG0116; Bacteria.
DR HOGENOM; CLU_032119_3_1_9; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000001383; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000001383};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 42..153
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 372 AA; 41696 MW; C958F5D822CE004E CRC64;
MYQLLATTPM GMEAVAAKEV QALGYETVTE NGRVLYQGDA RAIVKSNLWL RSADRVKLVV
GRFYATTFEQ LFDKTKDIPW EDFISENGQF PVQGRSLKSK LFSVPDCQAI VKKAIVERLK
KAHNKQGWLS ESGALYKVEV AILKDEVLLT IDTSGAGLHK RGYRLAQGEA PMKETLAAAL
VLLSNWKGDT PFIDPFCGSG TIAIEAAMIA QNIAPGFNRD FVSENWDIVP AGMYEEERVL
AEEAADYDKE ISITASDIDP NMVEIARNNA IEVGFGDIIK FKQMNVHDLT LNDEKGAIVG
NPPYGERIGE RAEVEAMYSY LGELIEKNPK WSLYILTSLK TFEVLVGKKA TKRRKLFNGY
IECTYYQYWG ER
//
