ID B9EC88_MACCJ Unreviewed; 250 AA.
AC B9EC88;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=Class A sortase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=MCCL_plsB0018 {ECO:0000313|EMBL:BAH18696.1};
OS Macrococcus caseolyticus (strain JCSC5402).
OG Plasmid pMCCL2 {ECO:0000313|EMBL:BAH18696.1,
OG ECO:0000313|Proteomes:UP000001383}.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Macrococcus.
OX NCBI_TaxID=458233 {ECO:0000313|EMBL:BAH18696.1, ECO:0000313|Proteomes:UP000001383};
RN [1] {ECO:0000313|EMBL:BAH18696.1, ECO:0000313|Proteomes:UP000001383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCSC5402 {ECO:0000313|EMBL:BAH18696.1,
RC ECO:0000313|Proteomes:UP000001383};
RC PLASMID=pMCCL2 {ECO:0000313|EMBL:BAH18696.1,
RC ECO:0000313|Proteomes:UP000001383};
RX PubMed=19074389; DOI=10.1128/JB.01058-08;
RA Baba T., Kuwahara-Arai K., Uchiyama I., Takeuchi F., Ito T., Hiramatsu K.;
RT "Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402,
RT reflecting the ancestral genome of the human-pathogenic staphylococci.";
RL J. Bacteriol. 191:1180-1190(2009).
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DR EMBL; AP009486; BAH18696.1; -; Genomic_DNA.
DR AlphaFoldDB; B9EC88; -.
DR MEROPS; C60.006; -.
DR KEGG; mcl:MCCL_plsB0018; -.
DR HOGENOM; CLU_045680_4_2_9; -.
DR Proteomes; UP000001383; Plasmid pMCCL2.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06165; Sortase_A; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR042007; Sortase_A.
DR InterPro; IPR023365; Sortase_dom-sf.
DR NCBIfam; TIGR01076; sortase_fam; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Plasmid {ECO:0000313|EMBL:BAH18696.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000001383};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT REGION 61..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 167
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 229
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 250 AA; 28229 MW; EB0B9B4EB788AFBD CRC64;
MNKNKIIKFL FILFIIVGLL ISATPYVINN FIEPYHMNRI HEETINVSKG TIKENKKKIN
AMQQATDDSI SSTNNNGTAD KNNIGYQENT ENYDSISYDP SAIQSLSRIP KFQEVNMNFL
VGYIQIPEVN LELPVLEGLT NENLNVATGT MKPGQEMGKR NYAIAGHHMP NENLLFSPLM
RVKKGNLVYL TDKDRTYVYK VIKTEVLDVN RGDVVADAEG DKIITLITCT DIKGTARWMV
RGKLIKTINN
//
