ID B9HY06_POPTR Unreviewed; 530 AA.
AC B9HY06;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 2.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=Apyrase 6 {ECO:0008006|Google:ProtNLM};
GN ORFNames=POPTR_010G169100 {ECO:0000313|EMBL:PNT17007.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT17007.1, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT17007.1, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
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DR EMBL; CM009299; PNT17007.1; -; Genomic_DNA.
DR RefSeq; XP_002315051.2; XM_002315015.2.
DR AlphaFoldDB; B9HY06; -.
DR EnsemblPlants; Potri.010G169100.2.v4.1; Potri.010G169100.2.v4.1; Potri.010G169100.v4.1.
DR GeneID; 7481587; -.
DR Gramene; Potri.010G169100.2.v4.1; Potri.010G169100.2.v4.1; Potri.010G169100.v4.1.
DR KEGG; pop:7481587; -.
DR eggNOG; KOG1386; Eukaryota.
DR HOGENOM; CLU_010246_5_1_1; -.
DR OrthoDB; 180318at2759; -.
DR Proteomes; UP000006729; Chromosome 10.
DR ExpressionAtlas; B9HY06; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF3; APYRASE 6-RELATED; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 188
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 218..222
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 530 AA; 58809 MW; 7A668B59342FDFFE CRC64;
MRRLHVRNRV GSNSTDQTDQ HKMDPAIKLH TRSIKSKLIT IITLIVLLSC YYLFKSKTKS
FSKKYGIIID GGSTGTRIHV FGYRIGSGGK AVFDFEEGAL KVNPGLSAYA EDPEGAGGSV
EELVEFGKGR VPRELWGETE VRLMATAGVR LLDLEVQDQI LNVCRRVLRK SGFKFQDSWA
SVITGSDEGL YAWVVANYAL GALGGDPLET SGIIELGGAS AQVTFVSTEP VPPEFSRTIK
FGNISYNIYS HSFLHLGQIA AFEALRESLV SGDHHLAAES LEKGIFKDPC TPKGYSHVVE
SWKLSPGSLT EKNRFVSTLH SRGNFSECRS AALTLLQKGK ERCSYQHCHI GSIFVPKLQG
KFLATENFFH TSKFFGLDQR AFLLNLMIAG EQFCGEDWSR LKKKHQSFKD EDLALYCFSA
AYIVALLHDS LGIAIDDQRI GFANQVGNIP LDWASGAFIL YTNAALDMEE HSDWIVTIIS
DDPLTLLSLI GIAIVLIFVA WPISKWGKHQ LKTFYDLERG WYIVTRGGKS
//
