ID B9I8P4_POPTR Unreviewed; 656 AA.
AC B9I8P4;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 3.
DT 24-JAN-2024, entry version 77.
DE RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein {ECO:0000259|Pfam:PF02826};
GN ORFNames=POPTR_014G089400 {ECO:0000313|EMBL:PNT03798.2};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT03798.2, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT03798.2, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
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DR EMBL; CM009303; PNT03798.2; -; Genomic_DNA.
DR AlphaFoldDB; B9I8P4; -.
DR SMR; B9I8P4; -.
DR STRING; 3694.B9I8P4; -.
DR EnsemblPlants; Potri.014G089400.1.v4.1; Potri.014G089400.1.v4.1; Potri.014G089400.v4.1.
DR Gramene; Potri.014G089400.1.v4.1; Potri.014G089400.1.v4.1; Potri.014G089400.v4.1.
DR eggNOG; KOG0067; Eukaryota.
DR HOGENOM; CLU_013739_0_0_1; -.
DR InParanoid; B9I8P4; -.
DR Proteomes; UP000006729; Chromosome 14.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR045015; AN-like.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43254:SF3; C-TERMINAL BINDING PROTEIN AN; 1.
DR PANTHER; PTHR43254; C-TERMINAL BINDING PROTEIN AN-RELATED; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006729}.
FT DOMAIN 141..324
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..452
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 72492 MW; 9C1CC9DF3DC00247 CRC64;
MSATTTRSLA TMSHRRNTNT PPPPQQQQQQ QQQQQRLPLV VTLNCIEDFA IEQDSLSGVA
LIEHVPLGRL SDGKIESAAA VLLHSLAYLP RAAQRRLRPY QLILCLGSAD RAVDSALAAD
LGLRLVHVDT SRAEEIADTV MALFLGLLRR THLLSRHALS ASGWLGSLQP LCRGMRRCRG
LVLGIVGRSA SARSLATRSL AFKMSVLYFD VHEGPGKLTR SSITFPLAAR RMDTLNDLLA
ASDLISLHCA LTNETVQIIN EECLQHIKPG AFLVNTGSSQ LLDDCALKQL LIDGTLAGCA
LDGAEGPQWM EAWVKEMPNV LILPRSADYS EEVWMEIREK AISILQSFFF DGIVPKNAVS
DEEGEESEIG DESEQFHRQD KESTLQDSVG EQLTDDIQLT PETSRKKVSG QSIESTSQAQ
GSGMSQNTTT RSDERRSRSG KKAKKRHGRQ KPRQKSDNPS QLEKESTSHQ EDDTAMSGSD
QVSSSRFASP EDSRSRKTPI ELMQESSSGQ LSRSGKRLSG KSDELLKDGH IIALYARDRP
ALHVSRQRAK GGGWFLDALS NVTKRDPAAQ FLVVFRNKDT IGLRSFAAGG KLLQINRRME
FVFTSHSFDV WESWMLEGSL DECRLVNCRN PLAILDARVE ILAAIAEDDG VTRWLD
//
