ID B9KEU4_CAMLR Unreviewed; 275 AA.
AC B9KEU4;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Chorismate mutase / prephenate dehydrogenase {ECO:0000313|EMBL:ACM63579.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:ACM63579.1};
DE EC=5.4.99.5 {ECO:0000313|EMBL:ACM63579.1};
GN Name=tyrA {ECO:0000313|EMBL:ACM63579.1};
GN OrderedLocusNames=Cla_0216 {ECO:0000313|EMBL:ACM63579.1};
OS Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=306263 {ECO:0000313|EMBL:ACM63579.1, ECO:0000313|Proteomes:UP000007727};
RN [1] {ECO:0000313|EMBL:ACM63579.1, ECO:0000313|Proteomes:UP000007727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RM2100 / D67 / ATCC BAA-1060
RC {ECO:0000313|Proteomes:UP000007727};
RX PubMed=18713059; DOI=10.1089/fpd.2008.0101;
RA Miller W.G., Wang G., Binnewies T.T., Parker C.T.;
RT "The complete genome sequence and analysis of the human pathogen
RT Campylobacter lari.";
RL Foodborne Pathog. Dis. 5:371-386(2008).
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DR EMBL; CP000932; ACM63579.1; -; Genomic_DNA.
DR RefSeq; WP_012660963.1; NC_012039.1.
DR AlphaFoldDB; B9KEU4; -.
DR STRING; 306263.Cla_0216; -.
DR GeneID; 7410939; -.
DR KEGG; cla:CLA_0216; -.
DR PATRIC; fig|306263.5.peg.215; -.
DR eggNOG; COG0287; Bacteria.
DR HOGENOM; CLU_055968_2_0_7; -.
DR Proteomes; UP000007727; Chromosome.
DR GO; GO:0004106; F:chorismate mutase activity; IEA:UniProtKB-EC.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:ACM63579.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ACM63579.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007727}.
FT DOMAIN 1..275
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 275 AA; 30976 MW; 7441621DCC83E9ED CRC64;
MKVGIIGLGL IGGSLGLSLR ENKLIDLVCG YDINKEFEQI ALERKLIDKI VTFEELKKCD
VIFLAIPVRA IVKILKEFQG ISKDCTIIEL GSTKEEIIKN LPSYLQSQFI AAHPMAGTEN
SGPNAAIKDL YKNAVCVLCD VQNADHIHQK RAIEIFSDLG MKLVFMDSIS HDHHASIISH
LPHVISFSLA NFVMKEENKK NIAHLGGPSF KDMCRIAKSN PQMWSGIFEQ NKQNLLNSID
LFQKELQECK KMIEKCDVNE LETWIKSANK LREIL
//
