ID B9KGT2_ANAMF Unreviewed; 318 AA.
AC B9KGT2;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Protein HflC {ECO:0000256|PIRNR:PIRNR005651};
GN Name=hflC {ECO:0000313|EMBL:ACM49636.1};
GN OrderedLocusNames=AMF_804 {ECO:0000313|EMBL:ACM49636.1};
OS Anaplasma marginale (strain Florida).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Anaplasma.
OX NCBI_TaxID=320483 {ECO:0000313|EMBL:ACM49636.1, ECO:0000313|Proteomes:UP000007307};
RN [1] {ECO:0000313|EMBL:ACM49636.1, ECO:0000313|Proteomes:UP000007307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Florida {ECO:0000313|EMBL:ACM49636.1,
RC ECO:0000313|Proteomes:UP000007307};
RX PubMed=19134224; DOI=10.1186/1471-2164-10-16;
RA Dark M.J., Herndon D.R., Kappmeyer L.S., Gonzales M.P., Nordeen E.,
RA Palmer G.H., Knowles D.P. Jr., Brayton K.A.;
RT "Conservation in the face of diversity: multistrain analysis of an
RT intracellular bacterium.";
RL BMC Genomics 10:16-16(2009).
CC -!- FUNCTION: HflC and HflK could regulate a protease.
CC {ECO:0000256|PIRNR:PIRNR005651}.
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflC subfamily.
CC {ECO:0000256|ARBA:ARBA00007862, ECO:0000256|PIRNR:PIRNR005651}.
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DR EMBL; CP001079; ACM49636.1; -; Genomic_DNA.
DR AlphaFoldDB; B9KGT2; -.
DR STRING; 320483.AMF_804; -.
DR MEROPS; I87.001; -.
DR KEGG; amf:AMF_804; -.
DR eggNOG; COG0330; Bacteria.
DR HOGENOM; CLU_059167_1_0_5; -.
DR Proteomes; UP000007307; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd03405; SPFH_HflC; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR010200; HflC.
DR InterPro; IPR001972; Stomatin_HflK_fam.
DR PANTHER; PTHR42911; MODULATOR OF FTSH PROTEASE HFLC; 1.
DR PANTHER; PTHR42911:SF1; MODULATOR OF FTSH PROTEASE HFLC; 1.
DR Pfam; PF01145; Band_7; 1.
DR PIRSF; PIRSF005651; HflC; 1.
DR PRINTS; PR00721; STOMATIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007307};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..214
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
SQ SEQUENCE 318 AA; 35836 MW; 63A5115E6657B2F1 CRC64;
MLLTTSKACS PTCPWPERVA RKLEAGGSMK LSLARLALLG AIVFGLVTLA LESAFIVDEA
HQAIVVQFGR VQKSVQKSGL FYKVPVISEV IYFDKRIIEI RSDSCEVIAA DQKRFVVDFY
AKYKIIDPVK FYQTVRSETG LENRLGSIIE SSLRAQVGSV ALINFLNEAR ADVMRRIQEG
VSTESEKFGV EMVDVRIKRA DLPEENSAAI FRRMQTDREK EAREIRAEGE EMSQKIRSDA
DFQTRVIIAD AMRDAQIIRG TGDAKASQIY NNALKADPDF FSFYRTMRAY RRVFSDGTTK
IVLSPNNDFI SLFNKSRG
//
