ID   B9L3M6_THERP            Unreviewed;      1143 AA.
AC   B9L3M6;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:ACM06802.1};
DE            EC=3.6.1.- {ECO:0000313|EMBL:ACM06802.1};
GN   OrderedLocusNames=trd_A0390 {ECO:0000313|EMBL:ACM06802.1};
OS   Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2).
OG   Plasmid Tros {ECO:0000313|Proteomes:UP000000447}.
OC   Bacteria; Thermomicrobiota; Thermomicrobia; Thermomicrobiales;
OC   Thermomicrobiaceae; Thermomicrobium.
OX   NCBI_TaxID=309801 {ECO:0000313|EMBL:ACM06802.1, ECO:0000313|Proteomes:UP000000447};
RN   [1] {ECO:0000313|EMBL:ACM06802.1, ECO:0000313|Proteomes:UP000000447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27502 / DSM 5159 / P-2
RC   {ECO:0000313|Proteomes:UP000000447};
RC   PLASMID=Tros {ECO:0000313|Proteomes:UP000000447};
RX   PubMed=19148287; DOI=10.1371/journal.pone.0004207;
RA   Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A.,
RA   Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L.,
RA   Eisen J.A.;
RT   "Complete genome sequence of the aerobic CO-oxidizing thermophile
RT   Thermomicrobium roseum.";
RL   PLoS ONE 4:E4207-E4207(2009).
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DR   EMBL; CP001276; ACM06802.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9L3M6; -.
DR   KEGG; tro:trd_A0390; -.
DR   eggNOG; COG0514; Bacteria.
DR   HOGENOM; CLU_283406_0_0_0; -.
DR   OrthoDB; 9763310at2; -.
DR   Proteomes; UP000000447; Plasmid Tros.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17920; DEXHc_RecQ; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR   PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ACM06802.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ACM06802.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plasmid {ECO:0000313|EMBL:ACM06802.1}.
FT   DOMAIN          288..466
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          504..716
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1143 AA;  128144 MW;  C813395988A1BB64 CRC64;
     MTMPEARTSV EVRAWFWWFV RSLCGEGTLG STERNVLGVL PVPVRSALLR AVQEIDPDAL
     ESLDVRRAGL HAEDGNYVWV HSWRFAGGDE PTVLRRTARR PSVALELVGS FLEEFRAWQR
     AFLSLLRLAT EQGVRQLRVG VTGASLPVVE LAVADALATV ERASEFYGIT VALPDIELLC
     ASPRHVELAP FVSQVYRDHD GTVFVDLPRT PFACRVENRL PGQGIVFLDG WQSGSSETVE
     DSWWLAEQSL RLAALQQRPV GLRREVLDFF ARRFFRIPQL KEQQVTLIQR TLRGESSLGV
     LPTGFGKSLV FQLSALLLPS ATLVISPLRS LMRDQLLNLE QNGVVTAVAI TGSDSESEKR
     AKLEGLRTGR YRLVYVAPER LQIAGFLREL RSVGADHPIG LLVVDEAHCV SEWGHDFRPA
     YLRIPRLRQE LQEVAGRTIP IVGLTATASR LVRADILATL ELSEADVVQE TTSDRPNLSY
     SVHTPADLGA SEKEHALLRL LGERLPRTLR FTPNRLYFSA SPHKETGIVF CIYANPHGKT
     TLQEGVHWVA SVIAKHLFAE RRAIPVHAST PPTRCPSCRS PLWRSGSPHE CLKCGHKFEK
     PVGSPRWDEE VARIQDEFQR NEHPMLVATK GFGMGIDKPN IRYVVHYNLA SGIEAYYQEV
     GRAGRDGEHA HSALLYRPPH PDCRPQIAAA LGEPPCVVDR QAYRFYRCPF GLATLCDYGL
     QARFIRGNYP GVEEDTEETL KYWRFVREGR SIVVRTSQDD EELTRVQLAL YRLQLLGLVQ
     DFSLTYQRLT EVQIDAVPVR DWRTEDVLEG LRRYLQRTSV VLEQLSNGSS GSGAVSDLSV
     AFEGLVRQSR SLEREELVRR AVTILLTRVY QVVPPMRYQM LLNELDYATS HERGECRRLV
     LLARFDTTPP PDTYRCGFCD VCVPDLVFPP GKRAELPLVD VGLEELARRL PELLERYDGE
     RLRAFVEAVE RRGGVAGMLA RVTTRLEQEA TNVAALYLAG ALARRRPGRE REAWGYLERG
     IAEAIRQGLS REALLVFAEE AAELDALQTL VLLTGTGGPF DSLEGRQELL EYAVAALGEE
     AFQTRLLLAL LASERFLQQS EAILLPLERA LSRLASTVTF LEGLRERMEA SIVAGDGEHE
     REP
//