ID B9NSK6_9RHOB Unreviewed; 404 AA.
AC B9NSK6;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Cobalamin synthesis protein, P47K {ECO:0000313|EMBL:EEE37416.1};
GN ORFNames=RKLH11_1252 {ECO:0000313|EMBL:EEE37416.1};
OS Rhodobacteraceae bacterium KLH11.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=467661 {ECO:0000313|EMBL:EEE37416.1, ECO:0000313|Proteomes:UP000005135};
RN [1] {ECO:0000313|Proteomes:UP000005135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLH11 {ECO:0000313|Proteomes:UP000005135};
RX PubMed=21742885; DOI=10.1128/jb.05556-11;
RA Zan J., Fricke W.F., Fuqua C., Ravel J., Hill R.T.;
RT "Genome Sequence of Ruegeria sp. Strain KLH11, an N-Acylhomoserine Lactone-
RT Producing Bacterium Isolated from the Marine Sponge Mycale laxissima.";
RL J. Bacteriol. 193:5011-5012(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; DS999531; EEE37416.1; -; Genomic_DNA.
DR AlphaFoldDB; B9NSK6; -.
DR STRING; 467661.RKLH11_1252; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_2_0_5; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000005135; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000005135}.
FT DOMAIN 259..374
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 404 AA; 44883 MW; 759EF84165262F3A CRC64;
MSDERLPVTV LSGFLGAGKT TLLNRVLNNR DGRRVAVIVN DMSEVNIDAD LVRADTELSR
TDETLVEMSN GCICCTLRDD LLDEVRRLAA EGRFDYLLIE STGISEPLPV AATFDFRDEF
GESLSDVARL DTMVTVVDAV NLLNDYASHD FLSDRGETMG EEDERTLVHL LTDQIEFADV
VILNKVDDAG TDKVDAARKI IRSLNADAEI IETNQSRVAA EKILDTGLFD FDQAHEHPMW
AKELYGFADH VPETEEYGVT SYVYRAKAPF IPEKILAVLN GDMPGVIRAK GHFWIATRPE
WVAEFSLAGS LSSVKPIGTW WANVPQDRWP EHVATSDYIK QHWAEPWGDR RQELVFIGAG
IDWSALKAKL DACLVPAVLA GGPDALPLDL PDPFPGWRRV EDAA
//
