ID B9PSD9_TOXGV Unreviewed; 704 AA.
AC B9PSD9; A0A0F7UV25; B9QG76; S7UN70;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN ORFNames=BN1205_033850 {ECO:0000313|EMBL:CEL72892.1}, TGVEG_286660
GN {ECO:0000313|EMBL:ESS30674.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS30674.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS30674.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS30674.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS30674.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS30674.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL72892.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL72892.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
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DR EMBL; LN714494; CEL72892.1; -; Genomic_DNA.
DR EMBL; AAYL02000231; ESS30674.1; -; Genomic_DNA.
DR AlphaFoldDB; B9PSD9; -.
DR STRING; 432359.B9PSD9; -.
DR PaxDb; 5811-TGME49_086660; -.
DR EnsemblProtists; ESS30674; ESS30674; TGVEG_286660.
DR VEuPathDB; ToxoDB:TGVEG_286660; -.
DR eggNOG; KOG0244; Eukaryota.
DR OMA; QNTDAGM; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226}.
FT DOMAIN 66..406
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 495..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 152..159
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 704 AA; 76091 MW; 927563D2ECC110E7 CRC64;
MLMAAVSCPV APAVPLVTIS TIDTPLRKRN QVGLKKFSYA CVIPFCSSNT LLVFLFSGKA
APVAKGCVVC VRVRPESIQE ISSGGTICVS TKQTGDGSAT LLLTGLRDHQ YSFRYDFVFD
QDATQENVYC STCLPLVDKL LAGYSASVIA YGQTGAGKSY TMIGDCSSED FHSNLTDPTT
RGVIPRILEA LVRRTETLSQ QNSDTAFSIR GSLIEIYNET VRDLLAPGRD NLVIRESTPA
TVITDATEVP ISCPAQALEV IKAGFANRAL GTTLSNDKSS RSHAVLQITI QRDSILDCTT
KSSQLFLVDL AGSERVSKAD TAGDRLRETQ NINRSLLALG NVISAVPPTG GSRKHIPYRE
SKLTRLLQHS LGGNAFTVVL LCCSPHSFNV RETLSTLRFG DRAAHIHNKP QATETLSPML
LQKRLVESQT QLRFSQARLR ACVTQSARRI EAIKMLQKYI PEGVQLSDED TALLRKAIED
CTVLNSFVDS AASAASPKKL VSAPKSKPRV PLTLGASSSP SRQAAAHPDV AYSRPKEFVN
AGGHMPRSDN VSSLTQGSEL RLTSSPPHGA FEIAPSHQAG QYLVTSRNSA HPKEKYLLKT
QKQQHPQSPV TGVGNFRQQV PEAVPQLPPK QRPAEFCAVV AGQNSDDKMI NQDPADAPQK
TPNADCNQNT DAGMFDRALL VGCPLATYRA LYPTSGQFLE TPLV
//
