ID B9PVV7_TOXGV Unreviewed; 357 AA.
AC B9PVV7; A0A0F7V3E1; B6KMJ0; B9Q6G9; S7UQX5; S8EZI8;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Putative replication factor C subunit 2 {ECO:0000313|EMBL:ESS31046.1};
DE EC=2.7.7.7 {ECO:0000313|EMBL:ESS31046.1};
DE SubName: Full=Replication factor C small subunit, putative {ECO:0000313|EMBL:CEL76970.1};
GN ORFNames=BN1205_060100 {ECO:0000313|EMBL:CEL76970.1}, TGVEG_237110
GN {ECO:0000313|EMBL:ESS31046.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS31046.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS31046.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS31046.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS31046.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS31046.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL76970.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL76970.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000256|ARBA:ARBA00005378}.
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DR EMBL; LN714500; CEL76970.1; -; Genomic_DNA.
DR EMBL; AAYL02000206; ESS31046.1; -; Genomic_DNA.
DR AlphaFoldDB; B9PVV7; -.
DR STRING; 432359.B9PVV7; -.
DR PaxDb; 5811-TGME49_037110; -.
DR EnsemblProtists; ESS31046; ESS31046; TGVEG_237110.
DR VEuPathDB; ToxoDB:TGVEG_237110; -.
DR eggNOG; KOG0989; Eukaryota.
DR OMA; GCQSGSF; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013748; Rep_factorC_C.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF20; REPLICATION FACTOR C SUBUNIT 4; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ESS31046.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Transferase {ECO:0000313|EMBL:ESS31046.1}.
FT DOMAIN 63..201
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 39797 MW; E79D600DE7C960DB CRC64;
MTAAVSASSV EKAPSPFSTA APPRVSSAQV VPWVEKYRPR RVEDMAHQVE PKKMLRRILE
TGNMPHLLFY GPPGTGKTSA ALALVRELFG REEAKNRLLE LNASDDRGIK VVRERIKQYT
KTNIAKGKIN PETGREMPTW KIVILDEADM MTQDAQSALR RIMEAFSRTT RFIIICNYVH
RIIDPIFSRC SPHRFEPVAR DAQEARIRHI CDSEGLVVTS GAVDALLRIS QGDLRRAVTL
LQSAASIYDD NLHEDAILEV AGQPPARIVT DFLRACQASP SQASSEVDNV ISQGWDVCLL
LQEMIRQVVV SPHLKDLQKA RVINDIAQKE FAVFQGASPY LQLLSLSLRI HDCLAAP
//
