ID B9RG82_RICCO Unreviewed; 894 AA.
AC B9RG82;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=RCOM_1452040 {ECO:0000313|EMBL:EEF49537.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; EQ973778; EEF49537.1; -; Genomic_DNA.
DR AlphaFoldDB; B9RG82; -.
DR STRING; 3988.B9RG82; -.
DR eggNOG; KOG1052; Eukaryota.
DR InParanoid; B9RG82; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR34836; OS06G0188250 PROTEIN; 1.
DR PANTHER; PTHR34836:SF1; OS09G0428600 PROTEIN; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 3.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 419..716
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 827..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..864
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 659..720
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 894 AA; 99373 MW; 51A4087B0CC18872 CRC64;
MVMANNKPSQ VKIGVVLDLD DDNCCGKIGL SCITMAVSDF YTIHSHYKTR LVIDIRDSNR
DVVLAATAAM DLTKNVQVQA IIGPSTSMQA NFVAQVGEKS QVPIISFSAS RPSLTSIRNS
YFFRATQNDR AQVNAISAIV QSFGWREAVP IYVDNEYGVG IISHLVNALQ VAGTRVPYLS
AFSPLASDEQ ILEELYKLKT TGTRVFIVHM FPSLGSRIFN KANEIGMTSE NYSWILTDGM
SNFLSSIDHS IFNSMSGRVL GVKLYIPNTK KLENFQARWK EKFNQDHQGM FNAELNIYGL
WAYDATMALA MAIEKAASTA TFGFETKKFS SNSLDLETFG VSQNGPILIE SLANTSFKGL
TGDFIFVNQQ LQSSNYQIVN VNDVGLREDG LWPPKKGFVS KLSLASSLQA VASTSVSKKL
RIGVPNRAFN EFMNVERDAK TNATIYVTIT ERRSFYVDFT LPYMEHGGVS IIVPIEDHRT
SRSWVFLKPL TWRLWVTSIC LYVFIAAVLW VLKNRNEELQ GSPSRQTGTR FSCSAIVFPH
KEKVARNLAS ITVVIWCILG FVLTQSYGAA LSSFLTVQQL QPTVNYVTEL IQKREKVGYQ
NGSFVFGVLK GLGFHDSQLV SCSPAEQCER LLSKGSKHGG IGAAFDEMPY TNLILAQSCS
KYSLVQPILD IQQFKTNGFG FVFPKGSSFA VEVSRAILKL KESYQMKKME DKWFGKQKHC
SLHASDVSVS TKLDLDSFQE LFWIAGVASS LALVIYTGLF VHEHRQVLTP PYSSASILSI
VQDLLRIINR KDSNFNSAEH DLAFGKIFNQ KENHTSGKNA VDIERDLNLP DSRATNAPTV
SITAESPGEQ GATSSENPDP SLNWKTPTDV VPHIELRNPN QERQTSSKTI QENR
//
