ID B9RHR8_RICCO Unreviewed; 454 AA.
AC B9RHR8;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Enhancer of polycomb-like protein {ECO:0000256|RuleBase:RU361124};
GN ORFNames=RCOM_1573120 {ECO:0000313|EMBL:EEF48690.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. Involved in gene silencing by neighboring
CC heterochromatin, blockage of the silencing spreading along the
CC chromosome, and required for cell cycle progression through G2/M.
CC {ECO:0000256|ARBA:ARBA00025513}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU361124}.
CC -!- SIMILARITY: Belongs to the enhancer of polycomb family.
CC {ECO:0000256|ARBA:ARBA00008035, ECO:0000256|RuleBase:RU361124}.
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DR EMBL; EQ973781; EEF48690.1; -; Genomic_DNA.
DR RefSeq; XP_002513287.1; XM_002513241.2.
DR AlphaFoldDB; B9RHR8; -.
DR STRING; 3988.B9RHR8; -.
DR eggNOG; KOG2261; Eukaryota.
DR InParanoid; B9RHR8; -.
DR OrthoDB; 1343374at2759; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032777; C:piccolo histone acetyltransferase complex; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR024943; Enhancer_polycomb.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR PANTHER; PTHR14898; ENHANCER OF POLYCOMB; 1.
DR PANTHER; PTHR14898:SF0; ENHANCER OF POLYCOMB-LIKE PROTEIN; 1.
DR Pfam; PF10513; EPL1; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU361124};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU361124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU361124}.
FT DOMAIN 27..139
FT /note="Enhancer of polycomb-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10513"
FT COILED 249..289
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 454 AA; 52738 MW; F61C808C03FF6EF9 CRC64;
MSRLSFRPRP LDIHKKLPIV KSVKDFEEDD TPTSTRNSQL IRLVSADLDT EVQQHIPSKK
LAPEIPTPQF VVVDTYERDY SRTFSQPTSY LRARGARAEL GEFVEYDLDN EDEDWLREFN
QDKKILFPER FESLLFKLEV LDHKARERAG VITPTLGSPI PVLLQFDAAS EAMQAQTQSI
RHAVFQSVYS YWKDKRERWQ KPILRRLQPP PPVNDTNPYN VFRPREKAHR LHTRRMQRRE
NNVQSFEKLR QVRRNLDQAK TILEVLIKRE EKKREAMENE VNLQRVQMKY KHETELLEDS
LVLPGFPPIS SKFASSEDEF VDSDDLANSR PRARLAASQN PPFMDSLTVP AGSVKQEFRR
RHSPYGWLNK MDPLEPILLF TKPLVPDKLA AAGIAPPVDS SSKNGASSPP YRFHGRIGRG
GRIIFDRWNP FLDTPIDIHN SFYMPPRSRP SAYN
//
