ID   B9RKM7_RICCO            Unreviewed;      1268 AA.
AC   B9RKM7;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN   ORFNames=RCOM_1051840 {ECO:0000313|EMBL:EEF48225.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   EMBL; EQ973784; EEF48225.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9RKM7; -.
DR   STRING; 3988.B9RKM7; -.
DR   eggNOG; KOG0167; Eukaryota.
DR   InParanoid; B9RKM7; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd16664; RING-Ubox_PUB; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR045210; RING-Ubox_PUB.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR47446; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   PANTHER; PTHR47446:SF2; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   Pfam; PF04564; U-box; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00504; Ubox; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS51698; U_BOX; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          413..488
FT                   /note="U-box"
FT                   /evidence="ECO:0000259|PROSITE:PS51698"
FT   REPEAT          1013..1046
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   1268 AA;  139790 MW;  6D56D145AB096946 CRC64;
     MTTAATSSQI LHQISSFLSE ALSQPDLRRH LFSILRNGTS PSNKTTSVKP LNLALETLEK
     ALSATNPFVQ SSSLRLAESL LLSYPETPFS SFLLSLLYSL TQQPTNASIS LLNIFYLDPL
     LARSEIAPLI FQELFLVHLL PVLDWFNEQR SRISSASFSM NMSYDDRDED SACDVSIILP
     SSKLLSKMSG GQALEFRELE GSYDDVLDEN CRVYAQYFKE ILKNNDENRV ITPPSLILKE
     TGKVDKLNGS EDKMIKTEEL GLKNGRYNPI WADGERSVEF FSFGGSSRSK FPPSSNPRRV
     SAKTLKNHYS RALTTSPAVI SDSELESSLD DNMVNSSSSE SEAELEVIVA NKNLVQFLTD
     LTMLLFLVIN IFSLSCRLCI ATPLTFLNLS VTISSTDHVM GDIDNHPGAG KHTPPKDFVC
     PITSHLLDDP VTLETGQTYE RRAIQEWISR GNSTCPITRQ ALHSNQLPKT NYVLKRLVAS
     WREQNPEFAS NQSETAPQKT EPNFKSTIIS PVTSPNSVIS QSAIDSTMSE LRQAITDLCM
     SEILSESEMA VLRIEQFWQE LNMDLDVQSM LSKPPVINGF VEILFNSLDP QVLKATVFLL
     SELGSRDKGV VQTLTRVESD VECIVALFKN GLWEAVVLIY LLRPSTMSLL EMDLVESLLT
     VIKKKEDMLK MCLKPKTAAV LLLGQILSSS EESIVISIVN AIVSTKVIES IAGCLEAECA
     EERIAAVGIL SRCMQEHGKC RNTISAKAEL APVLDSFLSA TDGERFEIVL FFSELVKLNR
     RTLSEQVLHI IKDEGPVSTM HSLVSFLQTA LQDQCPVVAG LLLQLDLLAE PRKMSIYREE
     AIDTLISCLR KSEFTAAQIA AADTIVSLQG RFTASGKSLS RAILLKRAGL SKSYRNLTRM
     EKLGNLSGEI EETSVCFQGL RDLTSYMRDI KKGLRELKKS SPLALEILKI LSEGHESSAE
     LWNHEQLAQA DCTENGEVLS VTCFKDKIFS GHSDGTIKIW TGRGSVLHLI QEIKEHTKAV
     TSLVVLQSGE RLYSGSLDRT ARVWSIGNEE LHCVQIHDMK DQVQSLVVAN SISCFIPQGA
     GVKVHSWNGG SKLLNSNKYV KCLTLIQGKL YCGCHDSSIQ EIDLATGTLV TIQHGSRKLL
     GKANPIHALQ VGNGLIYAAS SALDGAAVKI WNASNYGPAG SLPTTLEVRA IAVSSELIYL
     GSKGGNVEIW DQKKLSIIET LQTGTEGARI LCMALDSNEE MLVIGTSDGR IQVKDFSLFL
     HFPAIKQF
//