ID B9S370_RICCO Unreviewed; 1335 AA.
AC B9S370;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Helicase, putative {ECO:0000313|EMBL:EEF41852.1};
GN ORFNames=RCOM_0730930 {ECO:0000313|EMBL:EEF41852.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
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DR EMBL; EQ973857; EEF41852.1; -; Genomic_DNA.
DR STRING; 3988.B9S370; -.
DR eggNOG; KOG0947; Eukaryota.
DR InParanoid; B9S370; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0055087; C:Ski complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IBA:GO_Central.
DR GO; GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IBA:GO_Central.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF24; DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH11; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EEF41852.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 357..512
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 625..827
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 586..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 149563 MW; D1C51D8C6510175C CRC64;
MNRIQATNEL SFRVGFSGYS GHLRVEPLST VEGRTDPVKS LPDFILPPAF PRETRESIKE
YIEEEYLLPR LDSDVFSPEN AGRQWDFDWF EKANVLLNPS LPRAVVVPTW ESPFRRQKST
SEQGIWEPKS VQMDVSELIA QDSSSLPRIA GPAKDFVRGS INNRPFRPGG LDDSQSLEKI
LPAGAANGEW LREVLNGGPA QSIPPSLKKG LDLGDLKAYP SSWNVYKDQS PSDTASREKL
VCHSSKDEYL KSDVDVVPEV HLLKDESRKS DSEESKIDIQ GSVFETEVSV LDEILSVDSG
GLTSRSDGTG DGGGHKEKKG WALSGNSEWI AEHFYQLLPD TALDFPFELD TFQKEAIYYL
EKGDSVFVAA HTSAGKTVVA EYAFALASKH CTRAVYTAPI KTISNQKYRD FCGKFDVGLL
TGDVSLRPEA NCLIMTTEIL RSMLYRGADI IRDIEWVIFD EVHYVNDAER GVVWEEVIIM
LPRHVNIVLL SATVPNTVEF ADWIGRTKQK KIQVTGTTKR PVPLEHCLFY SGELYKICEN
ETFIPQGLRV AKDAHKKKNT SAVSSGSLAL RDGAHGKKRE YLNRNKQNKH FGSQNAGSFS
GTSWGNQNNG NGQNNWGSRR SEASLWLQLV NKLSKKSLLP VVIFCFSKNR CDKSADGMSG
TDLTSSSEKS EIRVFCDKAF SRLKGSDRNL PQIVRVQSLL RRGIGVHHAG LLPIVKEVVE
MLFCRGVIKV LFSTETFAMG VNAPARTVVF DTLRKFDGKE FRQLLPGEYT QMAGRAGRRG
LDKIGTVIVM CRDEIPDERD LKHVIVGSAT RLESQFRLTY IMILHLLRVE ELKVEDMLKR
SFAEFHTQKK LPETQQVLMR KLAQPTKAIE CIKGEPDIEE YYDMFLEAEE YSNQISEAVM
QSSAAQQFLT PGRVVVVKSQ SGQDHLLGVV VKGPSTSMKQ YIVLVLKPDL PSSTQISNLQ
DKKSGDIPKA YLLMPKSKRG EEEYFYSTAS RKGSGAVNIK LPYQGTAAGV NYEVRGMDNT
EFLCICARKL KIDQVGLLED VSNTAFSKTV QQLSELKSDG NKYPPALDPL TDLKMKDVNL
VEAYKKWTSL LQKMARNKCH GCIKLEEHLN LAKEIKKHKD EIDKLRFQMS DEALQQMPDF
QGRIDVLKEI GCIDADLVVQ IKGRVACEMN SGEELICTEC LFENQLDDLE PEEAVAIMSA
FVFQQRNTSE PSLTPKLSKA KKRLYDTAIR LGELQVKNKL QINPEEYAQE NLKFGLVEVV
YEWAKGTPFA DICELTDVPE GLIVRTIVRL DETCREFKNA ASIMGNSSLY KKMEAASNAI
KRDIVFAASL YITGV
//
