ID   B9S4N8_RICCO            Unreviewed;       488 AA.
AC   B9S4N8;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Hypoxia-inducible factor 1 alpha inhibitor, putative {ECO:0000313|EMBL:EEF41362.1};
GN   ORFNames=RCOM_0990470 {ECO:0000313|EMBL:EEF41362.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|ARBA:ARBA00001954};
CC   -!- SIMILARITY: Belongs to the JARID1 histone demethylase family.
CC       {ECO:0000256|ARBA:ARBA00006801}.
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DR   EMBL; EQ973866; EEF41362.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9S4N8; -.
DR   STRING; 3988.B9S4N8; -.
DR   eggNOG; ENOG502QT8Y; Eukaryota.
DR   InParanoid; B9S4N8; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IBA:GO_Central.
DR   CDD; cd02208; cupin_RmlC-like; 1.
DR   Gene3D; 2.60.120.650; Cupin; 1.
DR   InterPro; IPR041667; Cupin_8.
DR   InterPro; IPR003347; JmjC_dom.
DR   PANTHER; PTHR12461:SF97; BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7-RELATED; 1.
DR   PANTHER; PTHR12461; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED; 1.
DR   Pfam; PF13621; Cupin_8; 1.
DR   SMART; SM00558; JmjC; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS51184; JMJC; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT   DOMAIN          147..296
FT                   /note="JmjC"
FT                   /evidence="ECO:0000259|PROSITE:PS51184"
SQ   SEQUENCE   488 AA;  55214 MW;  ADA375F04C976D29 CRC64;
     MGEEIKQWRV KTFEKLPSAP VFASQIESEN VPAAFNGYTR QWKAFTKWNP ANGGLDYLQE
     RVGSSTIEAM LSRTAPVFYG DLRSHERVPF PFSTFIDFCK QRIAKEEGHQ PAVSDAEEQD
     HLISGDYAQQ VYLAQVPIMN TEDRERVQLA TLREDIQIPA FLESKELASI NLWMNNAHAR
     SSTHYDPHHN VLSIVAGRKQ VTLWPPSASP FLYPMPIYGE ASNHSSVALE NPDFSLYPRA
     QFSLEYSQKV VLHAGDALFI PEGWFHQVDS DDLTIAVNFW WRSNIMSSML EHMDAYYLRR
     ILRSHSGLFQ ACEEKDSQGK DKHHLNVLES FSLQALHELV SLVHDCVNLA DPSEPVTATN
     DSAVTANLLF PEDDAVAKFL GALDPHTLQN VLLSMAHNFP RTLEALVLHL LSPAGAEVLT
     RKFDEIDQQN TEEDRNKFYR VFYGAFDDQF AAMDAILNAK ESFAFQAFKN VLDKYLGVNS
     DVRKPSVG
//