ID B9S630_RICCO Unreviewed; 686 AA.
AC B9S630;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=SAM-dependent MTase DRM-type domain-containing protein {ECO:0000259|PROSITE:PS51680};
GN ORFNames=RCOM_1063380 {ECO:0000313|EMBL:EEF40939.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
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DR EMBL; EQ973877; EEF40939.1; -; Genomic_DNA.
DR AlphaFoldDB; B9S630; -.
DR SMR; B9S630; -.
DR STRING; 3988.B9S630; -.
DR eggNOG; ENOG502QVZV; Eukaryota.
DR InParanoid; B9S630; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0006306; P:DNA methylation; IBA:GO_Central.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR030380; SAM_MeTfrase_DRM.
DR PANTHER; PTHR23068:SF25; DNA (CYTOSINE-5)-METHYLTRANSFERASE DRM2; 1.
DR PANTHER; PTHR23068; DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR PROSITE; PS51679; SAM_MT_C5; 1.
DR PROSITE; PS51680; SAM_MT_DRM; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT DOMAIN 357..686
FT /note="SAM-dependent MTase DRM-type"
FT /evidence="ECO:0000259|PROSITE:PS51680"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 647
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 686 AA; 77364 MW; 4B80F4C35586003E CRC64;
MGVIVYCFRI TTCKPVYMEH KTLYLEILGI AVASKEMDGD SFCGEGDNFD WDSEDEREIE
NFGLTNSSCL AVPAVEATAR SVEKCLMGFS CILRHASSSV RSSGTKVMDH FVGMGFPEKM
VAEAIQENGE ENADLILETL LKFSTISSPS SSGSKLIDHF VGMGFDVEMV DRAIQENGEE
KTDSILETLL TYSVIEKSHQ EQPHVDSDHW SSEYEGSFLN DFSDIDSSEN EENGKSQPVE
GNTLRFLARM GYTTDEASIA LERCGPDANI AELTDFICAA QMAKAADASF PEEKPKIRHF
DDDYPKNKKR NYAEYDMWKK KKQMKLDKKL LNGDDELIRL PNPMLGFGVP TDPAIVTHRK
LPEAALGPPF FYYENVALAP KGVWQTISRF LYDVEPEFVD SKYFCAAARK RGYVHNLPIQ
NRYPLLPLPP NNIHEALPLT KRWWPSWDTR TKLNCLQTCV ASAKLTDRIR KALEDYEGEP
PLSIRKYVLD ECRKWNLLWV GRNKLAPLEP DEVEMLLGFP RNHTRGGGIS RTDRYKSLGN
SFQVDTVAYH LSVLKDMFPE GISLLSLFSG IGGAEVALHR LGIRLKRVVS VEISEVNRNI
MRCWWEQTNQ TGTLIDIADV HDLNADRLEQ LMSSFGGFDL VVGGSPCNNL AGSNRHHRDG
LEGKESSLFF DYCRILDLVK CIMTRN
//
