ID   B9S9C4_RICCO            Unreviewed;      1188 AA.
AC   B9S9C4;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Fanconi anemia, complementation group D2 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=RCOM_0973340 {ECO:0000313|EMBL:EEF39794.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
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DR   EMBL; EQ973896; EEF39794.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9S9C4; -.
DR   STRING; 3988.B9S9C4; -.
DR   eggNOG; KOG4712; Eukaryota.
DR   InParanoid; B9S9C4; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0000793; C:condensed chromosome; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0070182; F:DNA polymerase binding; IBA:GO_Central.
DR   GO; GO:1990918; P:double-strand break repair involved in meiotic recombination; IBA:GO_Central.
DR   GO; GO:0007129; P:homologous chromosome pairing at meiosis; IBA:GO_Central.
DR   GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR   GO; GO:0031573; P:mitotic intra-S DNA damage checkpoint signaling; IBA:GO_Central.
DR   InterPro; IPR029448; FANCD2.
DR   PANTHER; PTHR32086; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR   PANTHER; PTHR32086:SF0; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR   Pfam; PF14631; FancD2; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          658..684
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          711..731
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..677
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1188 AA;  131848 MW;  7A137E319CB6163D CRC64;
     MVFLHHQAPS RKRPSSSSSS SSFLSPLRPP KIPNSTAAEP PPSSSCSEND GVQAIDKMVS
     ILADAGCTLV NPSGPPCLPS DPLKLRSHLH RLFSSSDNVS ALRSIFLTGF SAYINSPKNL
     QRVLVSSNQY GSNESLLRQL LLVPPIQLDL QMLLLEKLPE FFSLGPECSL EDDVARLIIN
     QFRWLDFIVD SNAFCDKLMQ VLSICPLHLK KEIIGSLPEI MKDHNSKAVV DSLGQMLRED
     SSIVISALDC FSNLYLDDEL QEQVVTIAIS YIRTIDGEHM PHLLRFLLLS ATPQNVQRII
     SQIRQQLKFI GLSSNSHATQ SRKLQGKSLM DNTEASILDA LRTSLLFKNM LRQEIMRELI
     SLEKPQDHKV IDLWLLVLIH MNGDSTQKSI EKIFRKKVVD DCIQKVMIDQ CICGNKELVQ
     VLGALVTHVG SGVSFEVNSA LEAMALLASK YPQELIPFST HINGNLTDSL YVNSLLFIPI
     SNSISMVQVY EVFSHLALMA RSREECFGSS FANELLIILK KQVSHPDVKY KRMGLIGTLK
     IVSRLTDANE VGSTFQVERL TNGGSLGGID ALLGCPLHLP SSKLNAFCTQ VAQGFECISQ
     AMKEDIVAKL LKRLRNLVFL ESLLNNFIQG YPMCLPELFL HVQHSGTLSL DHANSTLHVE
     NKNEHKKTHD TASPDKRKHR KILKSSSSGI NGKLRQTTVF DVLKKGGAIT SQQSLHEDSS
     HQSLKTPVSA NQGSCTEPLI LEVPADTKTL DGHRSKFRPL LIQCFSLLEF SKLPLYLYLL
     GDLHNKLDYF TPGKEMPSRC MGPAPGFSRL ISEEFLSKVG PLFPNLRRHF ECALSVLKEV
     VKDTCEEHWK VHSASAGNPD IGNLVFSKSS VSISVSKEIL CCFRKFLNLP DVQMEKAVLS
     DLLEAFQSSK ISEVVLSSIQ PSPLPGTIEF LYLGASSFLE DVLNTASSIS FTLASESLLT
     LESLVASLHI FFDKSEKTGK STGSISIHRI LPTLRRSLGT SAQKLLRHNW GNGNLENGWK
     NKGEIVQKML HIYLENNESQ SDLLDELAAS IFPRVDSSGT ITEDNNLGFG MLCNETFVVW
     YRVLVLKKIA VTSKIPSTKR AIERFLFHVK ALLHATSNAR TFWMGNLKHK DLMGQVVGSQ
     VYGDDQDADV DGDLAEAEDN NQPISVASED KDHHLLNKLN ASLHYAEL
//