ID   B9SBS9_RICCO            Unreviewed;       341 AA.
AC   B9SBS9;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Cysteine protease, putative {ECO:0000313|EMBL:EEF38907.1};
DE            EC=1.3.1.74 {ECO:0000313|EMBL:EEF38907.1};
GN   ORFNames=RCOM_1043090 {ECO:0000313|EMBL:EEF38907.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
CC   -!- SIMILARITY: Belongs to the peptidase C1 family.
CC       {ECO:0000256|ARBA:ARBA00008455}.
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DR   EMBL; EQ973917; EEF38907.1; -; Genomic_DNA.
DR   RefSeq; XP_002523448.1; XM_002523402.2.
DR   AlphaFoldDB; B9SBS9; -.
DR   STRING; 3988.B9SBS9; -.
DR   MEROPS; C01.104; -.
DR   GeneID; 8282456; -.
DR   KEGG; rcu:8282456; -.
DR   eggNOG; KOG1543; Eukaryota.
DR   InParanoid; B9SBS9; -.
DR   OrthoDB; 5472443at2759; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0032440; F:2-alkenal reductase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR   GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR   CDD; cd02248; Peptidase_C1A; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR025661; Pept_asp_AS.
DR   InterPro; IPR000169; Pept_cys_AS.
DR   InterPro; IPR025660; Pept_his_AS.
DR   InterPro; IPR013128; Peptidase_C1A.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   InterPro; IPR039417; Peptidase_C1A_papain-like.
DR   InterPro; IPR013201; Prot_inhib_I29.
DR   PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR   PANTHER; PTHR12411:SF1032; SENESCENCE-SPECIFIC CYSTEINE PROTEASE SAG12; 1.
DR   Pfam; PF08246; Inhibitor_I29; 1.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   PRINTS; PR00705; PAPAIN.
DR   SMART; SM00848; Inhibitor_I29; 1.
DR   SMART; SM00645; Pept_C1; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR   PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR   PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Oxidoreductase {ECO:0000313|EMBL:EEF38907.1};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:EEF38907.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..341
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018548382"
FT   DOMAIN          38..95
FT                   /note="Cathepsin propeptide inhibitor"
FT                   /evidence="ECO:0000259|SMART:SM00848"
FT   DOMAIN          124..340
FT                   /note="Peptidase C1A papain C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00645"
SQ   SEQUENCE   341 AA;  37412 MW;  AB5740FBE3F9033A CRC64;
     MATISERKLM FVALLVVGLW VSQAWSRSLH DAAMNERHEM WMVKYGRVYK DNSEKERRFE
     IFRNNVEFIE SFNKPGNRPY KLDINEFADL TNEEFKASRN GYKRSSNVGL SEKSSFRYGN
     VTAVPTSMDW RQKGAVTPIK DQGQCGCCWA FSAVAAMEGI TKLSTGKLIS LSEQELVDCD
     TSGEDQGCEG GLMDDAFEFI KQNGGLTTEA NYPYQGTDGT CNTNKAGNDA AKITGYEDVP
     ANSEDALLKA VASQPVSVAI DASGSAFQFY SGGVFTGDCG TELDHGVTAV GYGTSDGTKY
     WLVKNSWGTS WGEDGYIRME RDIEAKEGLC GIAMQSSYPT A
//