ID B9SI83_RICCO Unreviewed; 857 AA.
AC B9SI83;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=3'-5' exonuclease, putative {ECO:0000313|EMBL:EEF36685.1};
GN ORFNames=RCOM_1321750 {ECO:0000313|EMBL:EEF36685.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
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DR EMBL; EQ973969; EEF36685.1; -; Genomic_DNA.
DR AlphaFoldDB; B9SI83; -.
DR STRING; 3988.B9SI83; -.
DR eggNOG; KOG2206; Eukaryota.
DR InParanoid; B9SI83; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IBA:GO_Central.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0071044; P:histone mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071040; P:nuclear polyadenylation-dependent antisense transcript catabolic process; IBA:GO_Central.
DR GO; GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IBA:GO_Central.
DR GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071036; P:nuclear polyadenylation-dependent snoRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071037; P:nuclear polyadenylation-dependent snRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IBA:GO_Central.
DR CDD; cd06147; Rrp6p_like_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR045092; Rrp6-like.
DR InterPro; IPR049559; Rrp6p-like_exo.
DR PANTHER; PTHR12124:SF47; EXOSOME COMPONENT 10; 1.
DR PANTHER; PTHR12124; POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:EEF36685.1};
KW Hydrolase {ECO:0000313|EMBL:EEF36685.1};
KW Nuclease {ECO:0000313|EMBL:EEF36685.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT DOMAIN 448..528
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..779
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..839
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 95975 MW; AA0ECBE6B8312777 CRC64;
MSQDAMNIDQ TAIQTQSKSQ TTTGSLSSSL SNLSGSSRTI PSNKDFHFYY NFDEFKLPIQ
QIARRSQSLL ESIGSSNNGL FKDKNLPYPN DPDNDDDTYW NVLMRLSMNL RVFKRNKRKK
KKKGLVSSVS GSPSGGSVSE SGVKVADLKA KGVKAKVPFH IPTIKKPQEE YNILVNNSNQ
PFEHVWLQRS EDGLRFIHPL EKLSILDFVD KSIGNAEPVS PPSLECTPFK LVKEVKDLKE
LAAKLRAVNE FAVDLEHNQY RSFQGLTCLM QISTRTEDFI IDTLKLRIHV GPYLREVFKD
PTKRKVMHGA DRDIIWLQRD FGIYVCNLFD TGQASRVLKL ERNSLEHLLR HFCGITANKE
YQNADWRLRP LTDEMLRYGR EDTHYLLYIY DLMRIMLLSM PNETENSNSP LAEVYKRSYD
VCMQLYEKEL LTESSYLHIY GLQTAGFNAQ QLAIVAGLCE WRDVIARTED ESTGFILPNK
TLLEIAKQMP VTPQKLRRAL KSKHPYIERN LGSVVNVVRH AMQNAAEFEA AAQRLKEGCI
ETDNLSSIFA FFMKASQDNV EVNDDMDMDT NLETAEAGTE TICDGSAVEG SENALQTDSP
QLKKEPLKAA LAIDATVQVL KKPAGAFGAL LGKSSAGKRR FDMAKKDKDE IKLDKIRSSV
SLPFHSFLGR KEPAKPAAEE PNLVTETPRP EESFAVPATG SSLEDIILLG DNSDVVVQEN
VDSDTKDVSK SVGCESETDE EGEPASLSDL STSFQKCFQS NNENKTNENN MQKSQDPTGL
LQLKPFDYAA ARKEVIFGEE SKAASGGKDQ SRNDGVKDRR KNSVGGGVEK DDGTRDFPQG
KRRQAFPATG NRSATFR
//
