ID B9T3L9_RICCO Unreviewed; 687 AA.
AC B9T3L9;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=RCOM_0178430 {ECO:0000313|EMBL:EEF29545.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EQ974426; EEF29545.1; -; Genomic_DNA.
DR RefSeq; XP_002532838.1; XM_002532792.2.
DR AlphaFoldDB; B9T3L9; -.
DR STRING; 3988.B9T3L9; -.
DR GeneID; 8278062; -.
DR KEGG; rcu:8278062; -.
DR eggNOG; KOG0584; Eukaryota.
DR InParanoid; B9T3L9; -.
DR OrthoDB; 53548at2759; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13983; STKc_WNK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR024678; Kinase_OSR1/WNK_CCT.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR13902; SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED; 1.
DR PANTHER; PTHR13902:SF120; SERINE_THREONINE-PROTEIN KINASE WNK8-RELATED; 1.
DR Pfam; PF12202; OSR1_C; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EEF29545.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEF29545.1}.
FT DOMAIN 22..284
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 687 AA; 77362 MW; D0C0D416B162DE93 CRC64;
MDLGLREDDD EYVEKDPTGR YLRYNEILGR GAFKTVYKAF DEVNGTEVAW NQVNIEDALN
SPDQLVRLYS SEVSLLKSLK HENIMKFFYS WIDDTKKNIN IITELFTSGS LSNYRKKHKN
VDIKAIKNWA RQILRGLHYL HSQNPPIIHR DLKCDNVFVN GNNGEVKIGD LGLALVMNPN
QPTAPTVMIG TPEFMAPELY LDEEYNELVD IYSFGMCVLE MVTCGYPYSE CKNKAQVYKK
VISGIKPASL GKVHDPQVQK FIEKCLVPSS KRLSAIELLN DPFLATGNSK ELEISASLQL
PSLLQSASYI INTGTNLKNL MAGSSIKGVR KDLEISALEI ERLVKKFEFR LRGEKIDDNA
VSFFLRIVDQ LSGRLNKIEF PFYLDSDTSL SIAEEMNEQF YLSNKDVGVI AEMIDALIMK
LAPGWSKSFG ISSTSNAPNG SSSGMKISSL EFQRSIEKFE FRLSGEQTYD NTVSCFLHII
EVQSSKSRKV EFSFYFDSDT SLSIAEGMTE ELDLFRELEF SSKDVATMIA EMIDALTMTL
VPSRRQVGSS STSSIQIDAM FKAISKQCFL PLPDMKGQET RDSFSSDSTI TSATNSNKPL
GSFDFSSFEY TSGSVSTLMM HDDDKYPESS GTSLPLANGD EQDELKMELN SIDMYYSQCF
QELLRMKEEA IRNAKENWIT TTKLPAT
//
