ID BFR2_CANAL Reviewed; 512 AA.
AC Q5ACL9; A0A1D8PU86;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 2.
DT 28-JUN-2023, entry version 81.
DE RecName: Full=Protein BFR2;
GN Name=BFR2; OrderedLocusNames=CAALFM_CR10470CA; ORFNames=CaO19.7624;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AOW31696.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; CP017630; AOW31696.1; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_719385.1; XM_714292.1.
DR AlphaFoldDB; Q5ACL9; -.
DR SMR; Q5ACL9; -.
DR STRING; 237561.Q5ACL9; -.
DR GeneID; 3638979; -.
DR KEGG; cal:CAALFM_CR10470CA; -.
DR eggNOG; KOG2773; Eukaryota.
DR HOGENOM; CLU_018299_2_2_1; -.
DR InParanoid; Q5ACL9; -.
DR OrthoDB; 26012at2759; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR025160; AATF.
DR InterPro; IPR039223; AATF/Bfr2.
DR InterPro; IPR012617; AATF_C.
DR PANTHER; PTHR15565; AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR15565:SF0; PROTEIN AATF; 1.
DR Pfam; PF13339; AATF-Che1; 1.
DR Pfam; PF08164; TRAUB; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome.
FT CHAIN 1..512
FT /note="Protein BFR2"
FT /id="PRO_0000056623"
FT REGION 1..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..136
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..502
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 58463 MW; 4C9BC3B87CD3A44A CRC64;
MAKKSLSEQI SSLYTPKTDY DIEDHDLDVS KDNGIFQHHD GGSENESEDE DTGLRNEHYV
ESSKSKLRQQ NEGVNLGEKY VGNVTSRSKL YDDEDDKQPT EASSGEELDA ESAEEEEDEE
SEDVADDDED DQESDRSSSS DAENDEDENI SHKRELLKQL MSKERSHIVN RLSQSATNDA
LKGYSIQQQN KTFEKIIDVR LKFQKSVTSS NMLPINTSTY SETKSEDSDE LVTKAKKQLY
SLLDHLFTLR NELDESTSVK TPKKRSFAKY SEVTSAADAQ LNSRRNQILT KWSAKVANSS
GRNAMNANKF KTINQSFEQQ VNNNLSDMDR LIKRTKLNRR NVTPIGYTTK EEDDHENGNK
NKSIDEDDDD IPEDTSVRKK TQGLENDYIF DDEDFYRVLL NDLVDKKVQT SDPTSGITIS
LRAAQKSNKL KNNVDTKASK GRKLRYHVQE PIANFETSRG SWRWNDDQID EFFASLLGQK
VNMNEIDDEQ EEEQENDDND IIPEDNGIQL FG
//
