ID BUK_EXIS2 Reviewed; 367 AA.
AC B1YLR4;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Probable butyrate kinase {ECO:0000255|HAMAP-Rule:MF_00542};
DE Short=BK {ECO:0000255|HAMAP-Rule:MF_00542};
DE EC=2.7.2.7 {ECO:0000255|HAMAP-Rule:MF_00542};
DE AltName: Full=Branched-chain carboxylic acid kinase {ECO:0000255|HAMAP-Rule:MF_00542};
GN Name=buk {ECO:0000255|HAMAP-Rule:MF_00542}; OrderedLocusNames=Exig_0917;
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + butanoate = ADP + butanoyl phosphate;
CC Xref=Rhea:RHEA:13585, ChEBI:CHEBI:17968, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:58079, ChEBI:CHEBI:456216; EC=2.7.2.7;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00542};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00542}.
CC -!- SIMILARITY: Belongs to the acetokinase family. {ECO:0000255|HAMAP-
CC Rule:MF_00542}.
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DR EMBL; CP001022; ACB60397.1; -; Genomic_DNA.
DR RefSeq; WP_012369821.1; NC_010556.1.
DR AlphaFoldDB; B1YLR4; -.
DR SMR; B1YLR4; -.
DR STRING; 262543.Exig_0917; -.
DR KEGG; esi:Exig_0917; -.
DR eggNOG; COG3426; Bacteria.
DR HOGENOM; CLU_048716_0_0_9; -.
DR OrthoDB; 9771859at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0047761; F:butyrate kinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.420.40; -; 2.
DR HAMAP; MF_00542; Butyrate_kinase; 1.
DR InterPro; IPR000890; Aliphatic_acid_kin_short-chain.
DR InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR011245; Butyrate_kin.
DR NCBIfam; TIGR02707; butyr_kinase; 1.
DR PANTHER; PTHR21060; ACETATE KINASE; 1.
DR PANTHER; PTHR21060:SF3; BUTYRATE KINASE 2-RELATED; 1.
DR Pfam; PF00871; Acetate_kinase; 1.
DR PIRSF; PIRSF036458; Butyrate_kin; 1.
DR PRINTS; PR00471; ACETATEKNASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome;
KW Transferase.
FT CHAIN 1..367
FT /note="Probable butyrate kinase"
FT /id="PRO_1000146589"
SQ SEQUENCE 367 AA; 39774 MW; 276530BC88603785 CRC64;
MSERILTINP GSTSTKIGIF DGTEQVFTKT LRHSAEAVGG PLSDQLNIRR QVVLDVLAQE
QIDLKALTAI VGRGGLLRPL VSGTYRVNQE MREDLLNGTF GIHASNLGGL LADEIGQTLS
IPAFIVDPVV VDELEPIARL TGLPELERKS IFHALNQKAV AKRYAKENGI PYEQLRLIVA
HMGGGITVGA HLNGRVIDVN NGLDGEGAFS PERSGSLPVG QLVELCYSTK YKLEEMKRLV
VGSGGLVAHL GTYDAVEIER RIDDGDEKAA LLYEAMAYRV AKEIAAQSAV LYGQVDAVIL
TGGLAYSDRL TKAIEERIAH IGSIIRIPGE DELRALAEGV IRVLRQEEQV KEYGGELTWL
ENSTSLS
//
