ID C0C0P3_9FIRM Unreviewed; 511 AA.
AC C0C0P3;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Xylulose kinase {ECO:0000256|RuleBase:RU364073};
DE Short=Xylulokinase {ECO:0000256|RuleBase:RU364073};
DE EC=2.7.1.17 {ECO:0000256|RuleBase:RU364073};
GN Name=xylB {ECO:0000256|RuleBase:RU364073};
GN ORFNames=CLOHYLEM_05647 {ECO:0000313|EMBL:EEG74380.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG74380.1, ECO:0000313|Proteomes:UP000004893};
RN [1] {ECO:0000313|EMBL:EEG74380.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG74380.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG74380.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG74380.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+);
CC Xref=Rhea:RHEA:10964, ChEBI:CHEBI:15378, ChEBI:CHEBI:17140,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57737, ChEBI:CHEBI:456216;
CC EC=2.7.1.17; Evidence={ECO:0000256|RuleBase:RU364073};
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|RuleBase:RU364073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG74380.1}.
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DR EMBL; ABYI02000020; EEG74380.1; -; Genomic_DNA.
DR RefSeq; WP_006442987.1; NZ_GG657759.1.
DR AlphaFoldDB; C0C0P3; -.
DR STRING; 553973.CLOHYLEM_05647; -.
DR eggNOG; COG1070; Bacteria.
DR HOGENOM; CLU_009281_3_0_9; -.
DR OrthoDB; 9805576at2; -.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004856; F:xylulokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0005997; P:xylulose metabolic process; IEA:InterPro.
DR CDD; cd07805; FGGY_XK_like_2; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR006000; Xylulokinase.
DR NCBIfam; TIGR01312; XylB; 1.
DR PANTHER; PTHR43095; SUGAR KINASE; 1.
DR PANTHER; PTHR43095:SF5; XYLULOSE KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU364073};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU364073};
KW Kinase {ECO:0000256|RuleBase:RU364073, ECO:0000313|EMBL:EEG74380.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU364073};
KW Transferase {ECO:0000256|RuleBase:RU364073};
KW Xylose metabolism {ECO:0000256|ARBA:ARBA00022629,
KW ECO:0000256|RuleBase:RU364073}.
FT DOMAIN 4..246
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 258..450
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 511 AA; 56941 MW; 8C39D17AC749B206 CRC64;
MDKYLIAHDL GTSSNKASLF STEGRLIKSY TVPYDVRFFQ KNCAEQNPLD WWNAVCTATR
KIVDGICPED VLSLSFSSQM QACVIVDRQG NALRPAMIWA DLRAEEQARQ LIERVGAERM
YELNGHRASA SYSIEKLMWI RDNEPELYGR TYKMLLAKDY IICRLTGNFV TDHSEASGTD
AFDLRNRRWS EEILSAAEIE MEKMPELNAS TDVVGQLLPE AAQALGLKKE TRVVCGGGDG
PCSALGAGSI EKGQMFLSFG TSAWIAGTSE EVFLDKEKTL ICFGHVIPGK YMPCGTMQAA
GSSYSYIRKT LCREEERRAQ DEGIPVYDIL NRLVTDSPAG ARGLVFLPYM LGERSPRWNP
DTSGSFLGIK MEHEKCDYIR AVLEGVAMNL DLILKAHREY THVEELVLTG GGAKGDVLAQ
ILSDVLGVAL RRLDYVETAT SVAAAVIAGV GVGVFEDFSV IHQFVKPERS FYPDRNNRDV
YARQKALFEE GYNCLRSYYE LETGFGKQST K
//
