ID C0C416_9FIRM Unreviewed; 679 AA.
AC C0C416;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Universal stress family protein {ECO:0000313|EMBL:EEG73090.1};
GN ORFNames=CLOHYLEM_06829 {ECO:0000313|EMBL:EEG73090.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG73090.1, ECO:0000313|Proteomes:UP000004893};
RN [1] {ECO:0000313|EMBL:EEG73090.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73090.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG73090.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73090.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG73090.1}.
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DR EMBL; ABYI02000032; EEG73090.1; -; Genomic_DNA.
DR RefSeq; WP_006444187.1; NZ_GG657759.1.
DR AlphaFoldDB; C0C416; -.
DR STRING; 553973.CLOHYLEM_06829; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_113_1_9; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02702; KdpD; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 408..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..236
FT /note="Signal transduction histidine kinase osmosensitive
FT K+ channel sensor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02702"
FT DOMAIN 409..516
FT /note="Sensor protein KdpD transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13493"
SQ SEQUENCE 679 AA; 77067 MW; 9BFE571B410D197C CRC64;
MDRDKRPDPR EVLEKIQAEE DKIRRKEYGK LKIFLGYAAG TGKTYAMLEE ALELRKNNID
VVAGYIEPHA RPETAALQEG LEHIPFLMKE YKGVNIREFD LDAALARRPK VLLVDELAHT
NVKGCRHEKR YQDIEELLEH GINVYTTVNI QHLESLNDNI AGITSIQMKE RIPDSIFDRA
DQVKLVDIEP EELIERMREG KIYGGIQAER ALQNFFTMDK LTALRETALR RMADRVNHLA
KEEKKLLGRG EYSAGEHVLT CISPAPSNAK VIRAAARLAY AFHAEFTALY VETKTIQNAS
EKVKKMRDEN IRLARTLGAK ITTVSGEDVA RQIAEYAKVS NVTKIVMGRT AHKIFFGQTR
KTLVESLNHY APNLDVYIIP DLQSGNGQKP PSFLKTEHCL KGLKKTDVLI LLFMLALGTA
AGFAFSAFHM SEANIIMAYL LCVMLTAINT EGYICSVLSS VFSVLLFNYF FIKPLHSLQA
YDTGYVFTFV MMLSVSLLTS WNMSNIQKQS KENAKRAYRT EILLMNSKKL RRVKGRRDIG
DELASQIQKL MNFTVIIYMK TGGRIQQPDV YLREGIRKEN RASLIQDYTS TEERAVVSWV
FENGHRAGCT THTLPYAKAI YLPVMDDDNV SAVVGMVLEE RREIAAFEYD LINAMLGEAA
LVFERFQKME DKTGDSLTK
//
