ID   C0D0S6_9FIRM            Unreviewed;       525 AA.
AC   C0D0S6;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Putative DNA mismatch repair protein MutS {ECO:0000313|EMBL:EEG55062.1};
DE   Flags: Fragment;
GN   ORFNames=CLOSTASPAR_02863 {ECO:0000313|EMBL:EEG55062.1};
OS   [Clostridium] asparagiforme DSM 15981.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Enterocloster.
OX   NCBI_TaxID=518636 {ECO:0000313|EMBL:EEG55062.1, ECO:0000313|Proteomes:UP000004756};
RN   [1] {ECO:0000313|EMBL:EEG55062.1, ECO:0000313|Proteomes:UP000004756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15981 {ECO:0000313|EMBL:EEG55062.1,
RC   ECO:0000313|Proteomes:UP000004756};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG55062.1, ECO:0000313|Proteomes:UP000004756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15981 {ECO:0000313|EMBL:EEG55062.1,
RC   ECO:0000313|Proteomes:UP000004756};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium asparagiforme (DSM 15981).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG55062.1}.
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DR   EMBL; ACCJ01000184; EEG55062.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0D0S6; -.
DR   HOGENOM; CLU_002472_9_2_9; -.
DR   Proteomes; UP000004756; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 1.10.1420.10; -; 2.
DR   Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR   Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR   InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR   InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR   InterPro; IPR036678; MutS_con_dom_sf.
DR   InterPro; IPR045076; MutS_family.
DR   PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   Pfam; PF01624; MutS_I; 1.
DR   Pfam; PF05188; MutS_II; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF05190; MutS_IV; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR   SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840}.
FT   DOMAIN          281..524
FT                   /note="DNA mismatch repair protein MutS core"
FT                   /evidence="ECO:0000259|SMART:SM00533"
FT   COILED          497..524
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         525
FT                   /evidence="ECO:0000313|EMBL:EEG55062.1"
SQ   SEQUENCE   525 AA;  60055 MW;  2A7E9A2F3CBF7D08 CRC64;
     MMQHYMETKK QYPDCVLFYR LGDFYEMFFD DALTVSKELE ITLTGKECGL PERAPMCGVP
     FHAVDSYLNR LVQKGYKVAI AEQMEDPKQA KGLVKREVIR VVTPGTITSA QALDETKNNY
     LMGIVCTDGG YGVSTADIST GDFLVTEVST DRELFDEINK FSPSEIICNN AFYVSGVDIE
     ELKNRYHVAV SALDSHFFGE ESCHKVLREH FRVGSLSGLG LEDYGTGIIA AGAVLQYMYE
     TQKSTLEHIT TIKPYSTGQF MIIDTSTRRN LELVETMREK QKRGTLLWVL DKTKTAMGAR
     LLRAYIEQPL IHREEIIARQ SAVEELNMNY ISREEIREYL NPVYDLERLI GRISYKTANP
     RDLISFCNSL EMLPYIKRLL EEFSSPLLKA LADDMDPLED LFELIRSAIV EEPPITLREG
     GIIRDGYNEE ADKLRAAKTE GKTWLAELEA REREKTGIKG LKVKFNKVFG YYFEVTNSFK
     NMVPDYFVRK QTLTNAERFT TDELKQLEEI IMGAEDKLVS LEYDL
//