ID   C0D9H7_9FIRM            Unreviewed;      1360 AA.
AC   C0D9H7;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=von Willebrand factor type A domain protein {ECO:0000313|EMBL:EEG52004.1};
GN   ORFNames=CLOSTASPAR_05927 {ECO:0000313|EMBL:EEG52004.1};
OS   [Clostridium] asparagiforme DSM 15981.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Enterocloster.
OX   NCBI_TaxID=518636 {ECO:0000313|EMBL:EEG52004.1, ECO:0000313|Proteomes:UP000004756};
RN   [1] {ECO:0000313|EMBL:EEG52004.1, ECO:0000313|Proteomes:UP000004756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15981 {ECO:0000313|EMBL:EEG52004.1,
RC   ECO:0000313|Proteomes:UP000004756};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG52004.1, ECO:0000313|Proteomes:UP000004756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15981 {ECO:0000313|EMBL:EEG52004.1,
RC   ECO:0000313|Proteomes:UP000004756};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium asparagiforme (DSM 15981).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG52004.1}.
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DR   EMBL; ACCJ01000494; EEG52004.1; -; Genomic_DNA.
DR   RefSeq; WP_007718048.1; NZ_GG657592.1.
DR   HOGENOM; CLU_259826_0_0_9; -.
DR   Proteomes; UP000004756; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        32..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          550..718
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   1360 AA;  149783 MW;  8B1B36FDD26A7218 CRC64;
     MSIWLQIGAG ILPALIILLL YLMIIRKNVV SSLILLFMFT AGLSLCVFHS KLPLSGGSRT
     ASWKAAPAEN TDAVKSAQAQ ADALPADETI RIIYGLAARK QTAEAAGMLK QLIADHGYDT
     SCALAQARIS AASGDFTAAR VLYEKAKTVW DDSAPREYNA VTEACASRSV DTVLLAHLDS
     SDIADLYPEG VPDTGDTGEA ARLVSDYLEQ AGSGGDADYS ELARVLASTQ ELYDTFLTSG
     EKDDSRIRSL EEDLDQWETD RPEVFSLKQV REARMRLKIL QGDYSSIAAD LTDESDYHEI
     MVASELYLNG YVKKSDFAGS YAQADDESLR TVTGQLRKIL NADIDPQTGK QVEELLNVYK
     NYKEDAPMYR MEQNLLSCTD ERGFTDSSKV YLQTAKMELL KDREDKAKEY IGLAMDTAAD
     CEDPEYTGPM YQIMGIMANK DEAESLKDVA LYTDNVLNNQ LEIVLPETVS ADSVQTQFSG
     YMTDYVSMQR SAVNISSLDA SAFSEITAYV QIETPVDYSI DELKSHITVE DCGAQISEYN
     LEKVEYSSAN MLLCCDVSGS MQGRPIEDSR AAVISMAESM SGNARLGVIL FNSSVQGLTD
     FTVQPDVIRS TAESMTANGG TNIFDTVVHG LESFPKNGPE VLNTLVVMSD GQENNAHSAE
     EIQTAIGQAA KDKSILVHCL GLGSEVDANY LQTIAQSAGG TYQYVTDSSS LAVFYQNLAS
     QQNYTYKLQY RATDTLSVDR ELKVSLNDSE YLYDIEAYTL PGENSAGESS GDGQHDLVYL
     GGLSIQGLDT RLLFKSVNPA TVHLLGTGFK KNDSVTVQMM MNNNGTHGLT YDVKAEFKDE
     NTFNLTIPPS VACGVYDVKV KIRGRTAYLD RELTVQVQGT EQTTAFGPYV FTSYQKQTVG
     DSTLLSGYVT LNNWLCFKGD LVLRGSLDNT QIQMEDSTGS YIRYYSGRSK GLAELLRSKN
     MVLPLPSLGT LKLYNDIQHN ASDKEYQVDV GIIPQLTFPS AFAMNTPGYS LYPDRLTINA
     MAFTTRFPFQ DKIFKPNDGK LFTFSVKEFG GILSPDNIDV TFNGELGGDS DIAYQTNFMS
     LPLKIRPSGK LNLDTLKDTY EISLYTKVLF FQEDENIGLS AKWDGKLIPA SMELMLPFKK
     TVVVSGVPIT FDNFRVGVDN FDITKWMEIT LVGKMDASAY SLKSLAPQVA EYIGDLSLLK
     LENSTLRLNY LGMEAKTTAK ILEHMEVGNA QLQLGNFPYT NQLLNMDSEN VYGIHGEVQL
     GVGLNTNNCD INLSGTGKIT VTNRFVGLSA DGDCHFYIHW WVLVNRFNAQ GMSTAGYFLD
     HDRVGTFTIR FRSSADNQKE QNFSISASKN GLYMNGKKVF
//