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Database: UniProt
Entry: C0DYT5_EIKCO
LinkDB: C0DYT5_EIKCO
Original site: C0DYT5_EIKCO 
ID   C0DYT5_EIKCO            Unreviewed;       283 AA.
AC   C0DYT5;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   08-MAY-2019, entry version 48.
DE   RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase {ECO:0000256|HAMAP-Rule:MF_00056};
DE            EC=2.5.1.55 {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=3-deoxy-D-manno-octulosonic acid 8-phosphate synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=KDO-8-phosphate synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE            Short=KDO 8-P synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE            Short=KDOPS {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=Phospho-2-dehydro-3-deoxyoctonate aldolase {ECO:0000256|HAMAP-Rule:MF_00056};
GN   Name=kdsA {ECO:0000256|HAMAP-Rule:MF_00056,
GN   ECO:0000313|EMBL:EEG22808.1};
GN   ORFNames=EIKCOROL_02551 {ECO:0000313|EMBL:EEG22808.1};
OS   Eikenella corrodens ATCC 23834.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
OC   Neisseriaceae; Eikenella.
OX   NCBI_TaxID=546274 {ECO:0000313|EMBL:EEG22808.1, ECO:0000313|Proteomes:UP000005837};
RN   [1] {ECO:0000313|EMBL:EEG22808.1, ECO:0000313|Proteomes:UP000005837}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23834 {ECO:0000313|EMBL:EEG22808.1,
RC   ECO:0000313|Proteomes:UP000005837};
RA   Fulton L., Clifton S., Chinwalla A.T., Mitreva M., Sodergren E.,
RA   Weinstock G., Clifton S., Dooling D.J., Fulton B., Minx P.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Mardis E.R.,
RA   Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-
CC         deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate;
CC         Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985;
CC         EC=2.5.1.55; Evidence={ECO:0000256|HAMAP-Rule:MF_00056,
CC         ECO:0000256|SAAS:SAAS01123735};
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis. {ECO:0000256|SAAS:SAAS00700395}.
CC   -!- PATHWAY: Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate
CC       biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-
CC       phosphate: step 2/3. {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00700401}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00700398}.
CC   -!- SIMILARITY: Belongs to the KdsA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00056, ECO:0000256|SAAS:SAAS00700400}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EEG22808.1}.
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DR   EMBL; ACEA01000057; EEG22808.1; -; Genomic_DNA.
DR   RefSeq; WP_003824838.1; NZ_EQ973323.1.
DR   STRING; 546274.EIKCOROL_02551; -.
DR   EnsemblBacteria; EEG22808; EEG22808; EIKCOROL_02551.
DR   GeneID; 29691588; -.
DR   eggNOG; ENOG4105CXR; Bacteria.
DR   eggNOG; COG2877; LUCA.
DR   OrthoDB; 687380at2; -.
DR   BioCyc; GCF_000158615-HMP:EIKCOROL_RS09995-MONOMER; -.
DR   UniPathway; UPA00030; -.
DR   UniPathway; UPA00357; UER00474.
DR   Proteomes; UP000005837; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019294; P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_00056; KDO8P_synth; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006269; KDO8P_synthase.
DR   PANTHER; PTHR21057; PTHR21057; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   TIGRFAMs; TIGR01362; KDO8P_synth; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005837};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00700397};
KW   Lipopolysaccharide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00700406};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:EEG22808.1}.
FT   DOMAIN       14    274       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   283 AA;  31220 MW;  D13081710998F043 CRC64;
     MQTALSQIPL HGFTIANHRP FVLFGGMNVL ESRDLAMEIA ETYIEICRKL DIPYVFKASF
     DKANRSSLHS FRGPGLEKGL QWLADIKAAY NVPVITDIHE PYQAAPAAEV ADILQLPAFL
     SRQTDLVHAM ARTGAIINVK KAQFLAPHEM RHIINKCLEA GNDKIILCER GSAFGYNNLV
     VDMLGFDTMK QMNVPVFFDV THSLQQPGAR SDSAGGRREQ IVTLARAGMA VGLAGLFLEA
     HPDPEQAKCD GPCALRLSQL EPFLNQLKQI DNLVKGFAEL DTH
//
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