ID   C0EHB3_9FIRM            Unreviewed;       743 AA.
AC   C0EHB3;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   SubName: Full=Putative stage V sporulation protein D {ECO:0000313|EMBL:EEG29200.1};
GN   ORFNames=CLOSTMETH_03313 {ECO:0000313|EMBL:EEG29200.1};
OS   [Clostridium] methylpentosum DSM 5476.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=537013 {ECO:0000313|EMBL:EEG29200.1, ECO:0000313|Proteomes:UP000003340};
RN   [1] {ECO:0000313|EMBL:EEG29200.1, ECO:0000313|Proteomes:UP000003340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5476 {ECO:0000313|EMBL:EEG29200.1,
RC   ECO:0000313|Proteomes:UP000003340};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG29200.1, ECO:0000313|Proteomes:UP000003340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5476 {ECO:0000313|EMBL:EEG29200.1,
RC   ECO:0000313|Proteomes:UP000003340};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium methylpentosum (DSM 5476).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG29200.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACEC01000115; EEG29200.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0EHB3; -.
DR   STRING; 537013.CLOSTMETH_03313; -.
DR   eggNOG; COG0768; Bacteria.
DR   HOGENOM; CLU_009289_6_0_9; -.
DR   Proteomes; UP000003340; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR   CDD; cd06577; PASTA_pknB; 1.
DR   Gene3D; 3.30.10.20; -; 2.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03793; PASTA; 2.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 2.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR   PROSITE; PS51178; PASTA; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003340};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          603..669
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
FT   DOMAIN          673..738
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   743 AA;  80161 MW;  EBEC39EC6243D6D8 CRC64;
     MAINPTRKMK FKLNIVVLGL LTLVFTILMG RILYISCFAQ VGGVKYGVKA YNQQLGADTI
     NANRGTIYDR NMNALARSAT VWTVSVAPNQ IDSDEKREKI ASGLADILGM DKEEILAKTQ
     KKNKYEIVKK KVEKPEADKI TEFVKENKLS GVHMVEDSRR YYPLGNTASH VIGFTGSDNQ
     GLAGVEIKYN DVLSGTPGKV VISQNALGTN MPFEYEYYYP AQDGNSLVLT LDQTLQHYVD
     KALKEAVDTH APGNRTCAIM MDVNNGEIVA MSTQPDFDLN DPFTITDPNL LATLEGKEGD
     ELKEAKSTAQ SRMWTNKAIS ETYEPGSVFK VVTSSAALEE KTMTLENTFD CSGSVQVAPG
     TTMKCWKAGG HGHESFVDAV VNSCNPAFIK IGASLGPDLF YQYFTQYGMT EKTGIDLPGE
     SKSLYVAKKD LGVVSLASES FGQSMSITPM QMLTAFCATV NGGYLVTPHV VKQVIDNDGN
     IVQSYDGKVR RQAISEETSE TMRYILEQVV SANGGSNASV PGYRIAGKSG TAQKLARRQE
     LGKDVYVSSF AGAVPADNPQ YALLVMVDEP TSGAYYGGAV ASPIFAEIMT DAIPYFGISP
     EYTEEELEHL AVSVPYLESF TVEEAKAKLS DAGLAAPEII GSGDTVIRQV PAAGSNVSKD
     ASVLLYTDDT DPNASMVTVP DVTNLTQEQA RIRLTNAGLN ISYSNTAVQN TKAMSTSQSP
     AAGESVPRGT VVTVEFLTND ETG
//