ID C0H9V0_SALSA Unreviewed; 545 AA.
AC C0H9V0;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=ADP-ribosylation factor GTPase-activating protein 3 {ECO:0000256|ARBA:ARBA00039243};
GN Name=ARFG3 {ECO:0000313|EMBL:ACN10819.1};
GN Synonyms=LOC106576371 {ECO:0000313|RefSeq:XP_014008977.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACN10819.1};
RN [1] {ECO:0000313|EMBL:ACN10819.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACN10819.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACN10819.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACN10819.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACN10819.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACN10819.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:XP_014008977.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014008977.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}.
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DR EMBL; BT059106; ACN10819.1; -; mRNA.
DR RefSeq; XP_014008977.1; XM_014153502.1.
DR STRING; 8030.ENSSSAP00000022553; -.
DR PaxDb; 8030-ENSSSAP00000022553; -.
DR GeneID; 106576371; -.
DR KEGG; sasa:106576371; -.
DR OMA; ENGPSKV; -.
DR OrthoDB; 389572at2759; -.
DR Proteomes; UP000087266; Chromosome ssa17.
DR Bgee; ENSSSAG00000014750; Expressed in ovary and 15 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR PANTHER; PTHR45686:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 2: Evidence at transcript level;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 10..126
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 163..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 59957 MW; 0F5A16B44E960400 CRC64;
MSEPSKQDIA AIFKRLRSLS TNKVCFDCSA KNPSWASITY GVFLCIDCSG THRSLGVHLS
FIRSTELDSN WSWYQLRCMQ VGGNASANAF FAQQGCTSNA ANTKYNSRAA VLYREKIKTS
ATQATRRFGT ELWLDSQAPL SPTSPVNKEE DFFSMHVQAF PDDRSSAQPN ITSSAQMNLS
PTPVEEPSTK ETEREKNGNT EGPSVDVLSM SPKEALESSL LKKKPAGAKK TLGAKKGGLG
GKKVSKQSFC DLEKKAQAVD KLNERDTAPT TTKNSPQPAE ESIGASMRLA YKDLEAQQRS
NTEKMKGMGE KKKEQAERLG MGFGSRSGVS HSVLSDMHTI QQESPVGSKQ PTKSRRYTEK
EEEETDEGSF TSRMSMTSSM TKFDEPTESS DKFFSNWSET GESGWRKESR KPEPDFYLST
KSSSQDDRTA ARRKADPVPV SDSGDARKKF GDVKAISSDM YFGKQDDSEY EAKTRLERFS
GSNSISSADL FDDPKKQMAS SYRLTNMLPS APDMSQLKLG VRSAAGRLSV MASGVVTSLQ
DHYSA
//
