ID C0HBT5_SALSA Unreviewed; 230 AA.
AC C0HBT5;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Heat shock factor protein 2 {ECO:0000313|EMBL:ACN11504.1, ECO:0000313|RefSeq:NP_001167375.1};
GN Name=HSF2 {ECO:0000313|EMBL:ACN11504.1};
GN Synonyms=hsf2 {ECO:0000313|RefSeq:NP_001167375.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACN11504.1};
RN [1] {ECO:0000313|EMBL:ACN11504.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACN11504.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACN11504.1, ECO:0000313|RefSeq:NP_001167375.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACN11504.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACN11504.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACN11504.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001167375.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC ECO:0000256|RuleBase:RU004020}.
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DR EMBL; BT059791; ACN11504.1; -; mRNA.
DR RefSeq; NP_001167375.1; NM_001173904.1.
DR GeneID; 100380619; -.
DR KEGG; sasa:100380619; -.
DR CTD; 3298; -.
DR OrthoDB; 1117127at2759; -.
DR Proteomes; UP000087266; Chromosome ssa06.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015:SF185; HEAT SHOCK FACTOR PROTEIN 2; 1.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Stress response {ECO:0000313|EMBL:ACN11504.1,
KW ECO:0000313|RefSeq:NP_001167375.1}.
FT DOMAIN 49..73
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
SQ SEQUENCE 230 AA; 27148 MW; 593A61C0CA3FA773 CRC64;
MKQNSNVPAF LTKLWTLVED SDTNEFICWS QEGNSFLVMN EQRFAKEILP KFFKHNNMAS
FVRQLNMYGF RKVMHIDTGI VKQERDGPVE FQHPYFKHGQ DDLLENIKRK VSNARPEDTK
IKQEDLSNIL ASVQNVNGKQ ESIDSRLNTL KRDNEGLWRE ISDLRQKHSQ QQQIIKKLIQ
FIVTFVQKNR IMGLKRKRPI LLNNNGKKPK YIHEIYDEPP LEHNKVCVEV
//
