ID C0IP18_BOVIN Unreviewed; 259 AA.
AC C0IP18; F1MXM8;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=CD209 molecule {ECO:0000313|Ensembl:ENSBTAP00000009621.5};
DE SubName: Full=DC-SIGN-like protein {ECO:0000313|EMBL:ACA13259.1};
GN Name=CD209 {ECO:0000313|Ensembl:ENSBTAP00000009621.5};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:ACA13259.1};
RN [1] {ECO:0000313|EMBL:ACA13259.1}
RP NUCLEOTIDE SEQUENCE.
RA Coffey T.J., Burt D., Werling D.;
RT "Identification and functional characterization of a bovine orthologue to
RT DC-SIGN.";
RL J. Leukoc. Biol. 0:0-0(2008).
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000009621.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000009621.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000009621.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000009621.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
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DR EMBL; EU431222; ACA13259.1; -; mRNA.
DR RefSeq; NP_001139228.1; NM_001145756.1.
DR STRING; 9913.ENSBTAP00000009621; -.
DR PaxDb; 9913-ENSBTAP00000009621; -.
DR Ensembl; ENSBTAT00000009621.6; ENSBTAP00000009621.5; ENSBTAG00000007312.6.
DR GeneID; 513266; -.
DR KEGG; bta:513266; -.
DR CTD; 30835; -.
DR VEuPathDB; HostDB:ENSBTAG00000007312; -.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT00940000162906; -.
DR HOGENOM; CLU_049894_7_3_1; -.
DR OMA; MAEMCDS; -.
DR OrthoDB; 3676313at2759; -.
DR TreeFam; TF333341; -.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000007312; Expressed in lung and 88 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR CDD; cd03590; CLECT_DC-SIGN_like; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR033989; CD209-like_CTLD.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR22802; C-TYPE LECTIN SUPERFAMILY MEMBER; 1.
DR PANTHER; PTHR22802:SF368; CD209F ANTIGEN; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lectin {ECO:0000256|ARBA:ARBA00022734}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 138..250
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 259 AA; 30057 MW; E457F5610ED3EC63 CRC64;
MAEMYEHKEP DDSEEETFGG QRLAERHPRP LHSLRSLSEC LTWGPLLLLL LLFVSLGFFT
LQLTTLVQVS RIQCLQRDSG DRENNSLDKW LDTRFRSLTE VAEKQMQSNL EKILQRLTRM
NATLAGLCHP CPQNWEFFDG SCYFFSWTQS DWRSAVSACL LIGAHLVIIE STEEEKFLNF
WYPRNNKPTW IGLSDHHSEG SWRWVDDSPV QLSFWKKGEP NNHGDEDCVE LHNDGWNDGR
CVTENPWICE KPSVPCPVL
//
