ID C0N702_9GAMM Unreviewed; 101 AA.
AC C0N702;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Cell division protein ZapA {ECO:0000256|ARBA:ARBA00015195};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000256|ARBA:ARBA00033158};
GN ORFNames=MDMS009_2218 {ECO:0000313|EMBL:EEF79631.1};
OS Methylophaga thiooxydans DMS010.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=637616 {ECO:0000313|EMBL:EEF79631.1, ECO:0000313|Proteomes:UP000004679};
RN [1] {ECO:0000313|EMBL:EEF79631.1, ECO:0000313|Proteomes:UP000004679}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMS010 {ECO:0000313|EMBL:EEF79631.1,
RC ECO:0000313|Proteomes:UP000004679};
RX PubMed=21478352; DOI=10.1128/JB.00388-11;
RA Boden R., Ferriera S., Johnson J., Kelly D.P., Murrell J.C., Schafer H.;
RT "Draft genome sequence of the chemolithoheterotrophic, halophilic
RT methylotroph Methylophaga thiooxydans DMS010.";
RL J. Bacteriol. 193:3154-3155(2011).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000256|ARBA:ARBA00024910}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ.
CC {ECO:0000256|ARBA:ARBA00026068}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC {ECO:0000256|ARBA:ARBA00010074}.
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DR EMBL; GG657899; EEF79631.1; -; Genomic_DNA.
DR RefSeq; WP_008291724.1; NZ_GG657899.1.
DR AlphaFoldDB; C0N702; -.
DR HOGENOM; CLU_116623_2_0_6; -.
DR OrthoDB; 5772359at2; -.
DR Proteomes; UP000004679; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.50; -; 1.
DR Gene3D; 3.30.160.880; Cell division protein ZapA protomer, N-terminal domain; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR042233; Cell_div_ZapA_N.
DR PANTHER; PTHR34981; CELL DIVISION PROTEIN ZAPA; 1.
DR PANTHER; PTHR34981:SF1; CELL DIVISION PROTEIN ZAPA; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; Cell division protein ZapA-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000004679};
KW Septation {ECO:0000256|ARBA:ARBA00023210}.
SQ SEQUENCE 101 AA; 11446 MW; 5DA8143CFCEC8189 CRC64;
MSSPVTVNIL GKEYQIACPE EEKEALMSSA RLVHDNMKKI RDSGKVVGVD RIAVMAALNL
AHELIVFQHD EGHDMEKVNN KIMQLKERVS AFLDEDRQLE L
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