ID   C0NC52_AJECG            Unreviewed;       374 AA.
AC   C0NC52;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   SubName: Full=NAD dependent epimerase/dehydratase {ECO:0000313|EMBL:EEH11243.1};
GN   ORFNames=HCBG_00698 {ECO:0000313|EMBL:EEH11243.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH11243.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663363; EEH11243.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NC52; -.
DR   STRING; 447093.C0NC52; -.
DR   VEuPathDB; FungiDB:I7I50_02623; -.
DR   HOGENOM; CLU_045030_1_0_1; -.
DR   InParanoid; C0NC52; -.
DR   OrthoDB; 5485209at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF11; LD23561P; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          10..239
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   374 AA;  41985 MW;  50C86BEAEAE52E87 CRC64;
     MSGEANKPAI LIVGGLGFLG RFLALHIHEN NLASEVRIVD KLLPQLAWLT PEFSAACSQD
     KFVQADASRE QSFSRIFDRA NGAQFDYVIN CGGESRLSQP DDVYRLRSHA LSVALGKEAA
     RRGIGAFIEC STATVYKSDR EPAKEDAKIK PWFAFSKWKY QAEEDLRKIP GLNLCILRFP
     HVYGEYDTGL LSTVICMGRA YMELGKPIPF LKTGSQPMNT VYVKDAARAM WRAAEWRASK
     GSIASGDPIV FNIVDHNKTT KNDLAQGLKK AFGIEYNFVG TMMTQVVNMN LDEIIDDMNE
     EGLQVWAELL NEKQIERPGP ISPFLERDSI KDGDLLIDGS LFEQTTGFTY ERPTLGEDWI
     QPVVESFKRL GWWP
//