ID   C0NFL6_AJECG            Unreviewed;       189 AA.
AC   C0NFL6;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase domain-containing protein {ECO:0000259|Pfam:PF09349};
GN   ORFNames=HCBG_01682 {ECO:0000313|EMBL:EEH10037.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH10037.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663364; EEH10037.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NFL6; -.
DR   STRING; 447093.C0NFL6; -.
DR   VEuPathDB; FungiDB:I7I50_00947; -.
DR   HOGENOM; CLU_092522_0_1_1; -.
DR   InParanoid; C0NFL6; -.
DR   OrthoDB; 903211at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3330.10; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; 1.
DR   InterPro; IPR018020; OHCU_decarboxylase.
DR   InterPro; IPR036778; OHCU_decarboxylase_sf.
DR   PANTHER; PTHR37987; CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE; 1.
DR   PANTHER; PTHR37987:SF1; OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF09349; OHCU_decarbox; 1.
DR   SUPFAM; SSF158694; UraD-Like; 1.
PE   4: Predicted;
KW   Purine metabolism {ECO:0000256|ARBA:ARBA00022631};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          13..182
FT                   /note="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
FT                   decarboxylase"
FT                   /evidence="ECO:0000259|Pfam:PF09349"
FT   REGION          86..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          170..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..130
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   189 AA;  21580 MW;  98BB858C71137CFB CRC64;
     MPSLPAISTV PFLPQATQTQ ILDTLFEASM DLHTLTLPLL IHQTFSSYQS LISAVGARMT
     ALSGADSPKD REVLYNILRA HPRLGEKKQE NLSELSRQEQ AALNAGREEG ERGDEGRDES
     QKRKAEEETA ELKKWNDLYE EKFPGLRYVV FVNGRGRDIL MQDMQRRIER DDIEKEKEDI
     IQTSPIPRN
//