ID C0NMA3_AJECG Unreviewed; 1454 AA.
AC C0NMA3;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=DEAH box polypeptide 36 {ECO:0000313|EMBL:EEH07754.1};
GN ORFNames=HCBG_04633 {ECO:0000313|EMBL:EEH07754.1};
OS Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS (Darling's disease fungus) (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH07754.1, ECO:0000313|Proteomes:UP000001631};
RN [1] {ECO:0000313|Proteomes:UP000001631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC {ECO:0000313|Proteomes:UP000001631};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG663367; EEH07754.1; -; Genomic_DNA.
DR AlphaFoldDB; C0NMA3; -.
DR STRING; 447093.C0NMA3; -.
DR VEuPathDB; FungiDB:I7I50_11088; -.
DR HOGENOM; CLU_001832_1_3_1; -.
DR InParanoid; C0NMA3; -.
DR OrthoDB; 1095660at2759; -.
DR Proteomes; UP000001631; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF197; DEPENDENT RNA HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07950)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT DOMAIN 666..837
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 926..1091
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1454 AA; 163536 MW; 6B5189E03FB94EBB CRC64;
MAPNRKKRKP ASNPARGFTT ISVPSKLKAP ESSTLLSSAS VPMERQPESR SQTASVGAQE
QPELQQLSPD ELQKHLEDAE LQLLVEKYGA KCKNDSSRQV LKLETEKRIL RPQASNLSVT
DWLSPEILNE IMEKEKLEIN QYREQISKAE MEETQICSEE ELSIKLWTLR ESLLGLGFTQ
LDVDEALKAT LKLSFNDSAA LKDIVWGLDQ SLEWLGMSCD ENDLPAYDKL RNNVSKIATK
DANLQTSNAS STPSSTGYNT SSDTRPKEQG IQAKTGLNLA CHSSDESDCD PDFLVPKYVE
IQTQLYVQQP DLFDKANKRL RKGVSSLTLE NDKTLVNAAK LKKKLSRIEN DILFDRDQAE
NMWQNKLAEL RKDTAKFLRN AVAEERQIEP PPAELTDTQI QDASDKLAES ICSGSNENDD
MLGGLFGADL EGPSAPSSSS GANGSTIIRN RDFGNPTGMN PRRVLEEACR ARDISPASFS
HRKEIEIRWS KAQDIAPQPP LGDISFRSDS HLVYASMASI STPTSLQAES YISTVALFAI
LSHSQKENKI YMKLPAVWRD LWDELIHVKK HYEDEVDKGI LKGIQKLVQE KMSTQEEDVI
LLGGFVKRNG GTNPPIPREN SVSKQTAKTH EQLQNLWTQR SSTSSFVSME SFRKTLPIWQ
FKDQILDTLA SNQAIIICSE TGSGKSTQVP SFILEKELLS GRDCKIYVTE PRRISAMSLA
KRLSDELGED KNAVGTNRSL VGYAIRLESK ISSSTRLIFA TTGVVVRMLE RPRDFEDITH
LVLDEVHERT IDSDFLLIIL RRLMQERPDL KLVLMSATVD AARFSKYLHG APVLDIPGRT
FPVEVKYLED AIEITKHCPN NDGLSALTDD DDELPDQSHD KPTGDLSSSL VGYSRQTREV
VTGIDEYRLD YKLIVSLLLA ITTRKEFEQY SKAILVFMPG MAEIRRLNDE ILSEPLFNKS
DWVIHALHSS IASEDQEKAF HIPPTGVRKI VIATNIAETG ITIPDITAVI DTGKEKVMRF
DEKRQLSKLV ESFIARANAK QRRGRAGRVQ RGLCFHLFTK FRHDKLLADQ QTPEILRLSL
QDLILRVKIC NLGEVEQTLS EAIDPPSPKN IRRAIEALKE VKALTNSEDL TPLGRLLAKL
PLDVFLGKLI IYGAFFKCLD SAVSIAAIVS SKSPFVNTVG SNTQRELAKL AFKRGNSDLL
TVYNAYLSWK RHRSTPGMSE HAFCRKNYLS SQTLQNIEDV KMQLLTSIVD SGLLNLDPAE
TDSLIRARFT GRQRQFFTVP KRMDINSEND IIVNSVIAWS FYPKLLIRNG KGWRNVANNQ
TVSLHPTSVN KKPDATLKWL SFYHIMQAGT RYLNAHETSP VEDFAIALLY GDVEFKLYAG
IIAIDGARIR FSVKDWKSML ALKALATRVR NALSFAIRNP HKELRSNQKG WVELWQKVFS
EAKERELRKN RSLF
//
