ID   C0NT46_AJECG            Unreviewed;      1187 AA.
AC   C0NT46;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Protein required for cell viability {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HCBG_06326 {ECO:0000313|EMBL:EEH05207.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH05207.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Tango6 family.
CC       {ECO:0000256|ARBA:ARBA00005724}.
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DR   EMBL; GG663371; EEH05207.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NT46; -.
DR   STRING; 447093.C0NT46; -.
DR   VEuPathDB; FungiDB:I7I50_05824; -.
DR   HOGENOM; CLU_006300_1_0_1; -.
DR   InParanoid; C0NT46; -.
DR   OrthoDB; 1424255at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019451; Rtp1_C1.
DR   InterPro; IPR019414; Rtp1_C2.
DR   InterPro; IPR039600; TANGO6/Rtp1.
DR   PANTHER; PTHR20959; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER; 1.
DR   PANTHER; PTHR20959:SF1; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG; 1.
DR   Pfam; PF10363; RTP1_C1; 1.
DR   Pfam; PF10304; RTP1_C2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          777..891
FT                   /note="RNA polymerase II assembly factor Rtp1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10363"
FT   DOMAIN          1096..1128
FT                   /note="RNA polymerase II assembly factor Rtp1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10304"
FT   REGION          911..938
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1162..1187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        919..938
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1187 AA;  130079 MW;  656628D5E6809CAC CRC64;
     MSDIKKDANR GENKSIRSEE RTAHTVVTYH NDITAQIMAM ECRQLVKAFD DAHEFLSPKS
     RGQSIVQILA RKLSVQGQGH GDATLHVIQR ALDLLVTIHR AYVDSNLDVG IDKSNGNGCR
     EDPVLEDTRR RRAIHGLLDL ISLEGIYPAL SQGVGIPLQQ RVMSTLPTGV VARQSEATSR
     DRSHDERLLR LIIDTLTPIV CHKHSGIQPI VMSRILGDIL CATAELAFHP HSLPQEQTSA
     YAELFQKLIE ESPTPTLLSI LSSFIQTSSA PWFKNIISSE LSHVPLRKDG VFHTIIFIAS
     QFEPALGQSA ETAPAQGPPI TVQAIMQISR LLSSVPQEIS ADDYFYNISP KLLALLDGDE
     PDLQKTASYV IGSGILGKRA LGEPGAIGYK IFVKPILDSL HGNMTTEVAA WLRRFSLDGS
     ALPASPLSDL ESVVLIDEPK LLLSLTRLSA LVLSHPNPSL LKRLIQPVFL PLWALGCYAK
     EHRKSSWYGK VSTLLQTFFS MSTGVSKYDN LSDNILWDGG RTWTFGPGQN GGVSIRKRTN
     SPAQQVLNTM LLMKILDDRI DGVLELLGLD PQSEELAGDI FLHVSRKWLL GHSGDHTQKE
     PEFLHGGEDL QTTLQKLTSA KFTEKLLNKF KDSLARRPDR ILGIVEQLIQ SEVSLRTKPA
     HGKLNNPSFQ SLGNIVENSQ GISDNDNPEQ SESLSASFSL LSTILASPDF FLSETLSPVI
     QRIKVQLDNL LPNLPSHLIQ PATTASMLLE MTLSSSLFPE RKPEAISSRI SDLEKHRQAL
     EHLSSPFPPI QAEGLTLLSC LITESSPVLD IPATLSLLLS LLSNSNIESS SNDEFVYLHV
     IKIIGVLASK HPRTVIGSLA ERYADRSEQH SLDQRLKIGE ALLRAVQELG NALVEDTART
     LGGTMVSVAG RRGRKPSAKR ARGEMAKKLT TQPTETEDDT LDREAADLMQ QIDEAMDSEV
     ENPALEAYSA NIIDAWAAGA ASDLEPDDLR IRASAMSILA SAIQTNVAGL GPSVVSSSVD
     LALSTLNFEQ GPESVILRRA AIILLLDLVK ALDTARENGI NLGFGFSYST TTNNDNQSTD
     FINPQPRYPN QGIIGNIPDI LRVLTFVETS ETDPVIRGHI RVLIESFEAW LEKSLLWGVR
     TREGIGEQPR FELGDRLAGL DIHPRVDGGG GSRHQLSGQG PRIEEIE
//