ID   C0NWN4_AJECG            Unreviewed;       376 AA.
AC   C0NWN4;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=2-nitropropane dioxygenase {ECO:0000313|EMBL:EEH04339.1};
GN   ORFNames=HCBG_07564 {ECO:0000313|EMBL:EEH04339.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH04339.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663374; EEH04339.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NWN4; -.
DR   STRING; 447093.C0NWN4; -.
DR   VEuPathDB; FungiDB:I7I50_08065; -.
DR   HOGENOM; CLU_038732_9_0_1; -.
DR   InParanoid; C0NWN4; -.
DR   OrthoDB; 1582275at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0018580; F:nitronate monooxygenase activity; IEA:InterPro.
DR   CDD; cd04730; NPD_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR004136; NMO.
DR   PANTHER; PTHR32332; 2-NITROPROPANE DIOXYGENASE; 1.
DR   PANTHER; PTHR32332:SF34; 2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED; 1.
DR   Pfam; PF03060; NMO; 1.
DR   SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE   4: Predicted;
KW   Dioxygenase {ECO:0000313|EMBL:EEH04339.1};
KW   Oxidoreductase {ECO:0000313|EMBL:EEH04339.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          15..356
FT                   /note="Nitronate monooxygenase"
FT                   /evidence="ECO:0000259|Pfam:PF03060"
SQ   SEQUENCE   376 AA;  39104 MW;  06E0D698ADFB7944 CRC64;
     MPTLHALHPT LPASTPAIIS APMLAIASPN LAVSVTRAGG LGFIGAGFGV SSLETLLSQA
     AELVSKPCSS PPIPNYTYKK DDDDDDDTSS SPLPIGIGLL NWGADLDLAL PVLAKQPPAA
     LWLFAARDPD PASTFAAWAR EVRRATHNRT RIWIQIGSVA EALEAAARAQ PDVLVVQGSD
     AGGHGLARSA SIVSLVPEVK DALVRAGHGG IPLVAAGGIA DGRGVAAALC LGAQGVVMGT
     RFLASAEAAV SRGYQAEVLR VADGGVSTVR TTVYDAVRGY NAWPAQYDGR GVVNETLRDK
     EAGMDDAENQ RLYKEEMAKG DAGWGPTGRM TTYAGTGIGL VREVKSAEEI VRGVVAEAKE
     ILEEVKGRLW GGLDEK
//