ID C0NZK8_AJECG Unreviewed; 365 AA.
AC C0NZK8;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000256|ARBA:ARBA00017307};
GN ORFNames=HCBG_08588 {ECO:0000313|EMBL:EEH03256.1};
OS Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS (Darling's disease fungus) (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH03256.1, ECO:0000313|Proteomes:UP000001631};
RN [1] {ECO:0000313|Proteomes:UP000001631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC {ECO:0000313|Proteomes:UP000001631};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF8 family.
CC {ECO:0000256|ARBA:ARBA00008767}.
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DR EMBL; GG663378; EEH03256.1; -; Genomic_DNA.
DR AlphaFoldDB; C0NZK8; -.
DR STRING; 447093.C0NZK8; -.
DR VEuPathDB; FungiDB:I7I50_00061; -.
DR HOGENOM; CLU_026584_0_0_1; -.
DR InParanoid; C0NZK8; -.
DR OrthoDB; 5483295at2759; -.
DR Proteomes; UP000001631; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR CDD; cd08049; TAF8; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037818; TAF8.
DR InterPro; IPR019473; TFIID_su8_C.
DR PANTHER; PTHR46469; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR PANTHER; PTHR46469:SF1; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF10406; TAF8_C; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001631};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 67..134
FT /note="Bromodomain associated"
FT /evidence="ECO:0000259|Pfam:PF07524"
FT DOMAIN 189..237
FT /note="Transcription factor TFIID subunit 8 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF10406"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..271
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 40286 MW; E39EF8775AAC4532 CRC64;
MSIPPPPTAS ASSPTKRPSS PLDAESTDHL ATKRQRRGYR HHHRLQTRMR PDLLPDSAFT
DPSTVDTLLK LSIGILLRDC GFTHADPVAL DSFRSAVEEY ILHILSYTRQ SMSSCRRMQP
IPPDFEHALR NTNIHLDALH EYLIPSLRQQ HQQIPSLPSP PPSSPTAAVD LPFLGPELSG
TAHRQLNVHI PKHFPNFPGR HTYRATPVFT ARETDPRKIR EKATEEGRLG EEALRKLARA
GREGLVVRDG ADANGDGHGE GEGEGGGGKR LWGRRLENME SMFEKTVRGV VGVGGGGRAA
GDAGLALPSS LKIPDNGKLE LSPIVNCDKV YWRKQTRADV RKTDQRMVHS NNDKGARGTL
VQQRV
//
