ID C0PAH7_MAIZE Unreviewed; 322 AA.
AC C0PAH7; A0A3L6EIY7; A0A3L6EL03; A0A8J8XFQ3;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 95.
DE SubName: Full=ADP-ribosylation factor GTPase-activating protein AGD12 {ECO:0000313|EMBL:AQK69569.1};
GN Name=100382772 {ECO:0000313|EnsemblPlants:Zm00001eb235980_P001};
GN ORFNames=ZEAMMB73_Zm00001d015804 {ECO:0000313|EMBL:AQK69569.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK69569.1};
RN [1] {ECO:0000313|EMBL:ACN31172.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B73 {ECO:0000313|EMBL:ACN31172.1};
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [2] {ECO:0000313|EnsemblPlants:Zm00001eb235980_P001, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb235980_P001,
RC ECO:0000313|Proteomes:UP000007305};
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [3] {ECO:0000313|EMBL:AQK69569.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK69569.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblPlants:Zm00001eb235980_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb235980_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
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DR EMBL; BT065296; ACN31172.1; -; mRNA.
DR EMBL; CM000781; AQK69563.1; -; Genomic_DNA.
DR EMBL; CM000781; AQK69564.1; -; Genomic_DNA.
DR EMBL; CM000781; AQK69569.1; -; Genomic_DNA.
DR EMBL; CM000781; AQK69570.1; -; Genomic_DNA.
DR RefSeq; NP_001168952.1; NM_001175481.1.
DR RefSeq; XP_008644019.1; XM_008645797.1.
DR RefSeq; XP_008644020.1; XM_008645798.1.
DR RefSeq; XP_008644021.1; XM_008645799.1.
DR AlphaFoldDB; C0PAH7; -.
DR SMR; C0PAH7; -.
DR IntAct; C0PAH7; 6.
DR PaxDb; 4577-GRMZM2G138349_P01; -.
DR EnsemblPlants; Zm00001eb235980_T001; Zm00001eb235980_P001; Zm00001eb235980.
DR EnsemblPlants; Zm00001eb235980_T003; Zm00001eb235980_P003; Zm00001eb235980.
DR GeneID; 100382772; -.
DR Gramene; Zm00001eb235980_T001; Zm00001eb235980_P001; Zm00001eb235980.
DR Gramene; Zm00001eb235980_T003; Zm00001eb235980_P003; Zm00001eb235980.
DR KEGG; zma:100382772; -.
DR eggNOG; KOG0703; Eukaryota.
DR eggNOG; KOG1030; Eukaryota.
DR HOGENOM; CLU_045472_0_1_1; -.
DR InParanoid; C0PAH7; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000007305; Chromosome 5.
DR ExpressionAtlas; C0PAH7; baseline and differential.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd04038; C2_ArfGAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR044518; ARF_GAP_AGD11/12/13.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR PANTHER; PTHR46220; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12; 1.
DR PANTHER; PTHR46220:SF17; OS02G0198300 PROTEIN; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF00168; C2; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50004; C2; 1.
PE 1: Evidence at protein level;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Proteomics identification {ECO:0007829|PeptideAtlas:C0PAH7};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 13..142
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 148..265
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 322 AA; 35066 MW; 4D8FA5B9F19E54C4 CRC64;
MSGHGDTATS AKMAKLKELL QKSENHICAD CGASDPKWAS ANIGVFICVK CSGVHRSLGT
HISKVLSVTL DKWSDSEVDS MIEVGGNSQA NAIYEAFIPE GYQKPHSDST QEEREKFIRS
KYELQEFLKP SLRIVSHQPS DSGKHAGNAS HSDGSKSQVG MIEFIGILNV KVIGGTNLAI
RDMSSSDPYV VLTLGQQKAQ TSVINGNLNP VWNEELKLSV PQQYGPLKLQ VFDHDMVSKD
DLMGEAEIDL QTMINAAAAF GDPELLGDIQ IGRWLKSEDN ALVRDSAVVV SGGKVKQGMA
LKLQHTESGE LELEMEWMPL NV
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