ID C0QL42_DESAH Unreviewed; 437 AA.
AC C0QL42;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Spk {ECO:0000313|EMBL:ACN14128.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:ACN14128.1};
GN Name=spk {ECO:0000313|EMBL:ACN14128.1};
GN OrderedLocusNames=HRM2_10160 {ECO:0000313|EMBL:ACN14128.1};
OS Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 /
OS HRM2) (Desulfobacterium autotrophicum).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulforapulum.
OX NCBI_TaxID=177437 {ECO:0000313|EMBL:ACN14128.1, ECO:0000313|Proteomes:UP000000442};
RN [1] {ECO:0000313|EMBL:ACN14128.1, ECO:0000313|Proteomes:UP000000442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43914 / DSM 3382 / HRM2
RC {ECO:0000313|Proteomes:UP000000442};
RX PubMed=19187283; DOI=10.1111/j.1462-2920.2008.01825.x;
RA Strittmatter A.W., Liesegang H., Rabus R., Decker I., Amann J., Andres S.,
RA Henne A., Fricke W.F., Martinez-Arias R., Bartels D., Goesmann A.,
RA Krause L., Puehler A., Klenk H.P., Richter M., Schuler M., Gloeckner F.O.,
RA Meyerdierks A., Gottschalk G., Amann R.;
RT "Genome sequence of Desulfobacterium autotrophicum HRM2, a marine sulfate
RT reducer oxidizing organic carbon completely to carbon dioxide.";
RL Environ. Microbiol. 11:1038-1055(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001087; ACN14128.1; -; Genomic_DNA.
DR RefSeq; WP_015902917.1; NC_012108.1.
DR AlphaFoldDB; C0QL42; -.
DR STRING; 177437.HRM2_10160; -.
DR KEGG; dat:HRM2_10160; -.
DR eggNOG; COG0515; Bacteria.
DR HOGENOM; CLU_626607_0_0_7; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000000442; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1.
DR PANTHER; PTHR44167:SF8; OVARIAN-SPECIFIC SERINE_THREONINE-PROTEIN KINASE LOK; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000442};
KW Transferase {ECO:0000313|EMBL:ACN14128.1}.
FT DOMAIN 174..422
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 437 AA; 49435 MW; DE7FFEE9BF1F14F8 CRC64;
MLSDTLLMLD LTEVEERLIQ QLTRPFEIRM MSIKPFDPQN NASLFHGKNI CMVILHAGPD
QTDTITGIHA IKKALKRPVP LLVLIPEVPP SPLNKFMKAG ADDYVVMPLD ADSFAMRFYV
LLECGQAILQ TQQDNEPDLD AWQVIVGYIQ EGLRFFTPKS QLTLKGRRPI SDRWIPEKRI
AVGGDAEIWL VQDRGKAKKA VAKIPHSPGM NVNALRAAAV LKRLVYHPNI VHLIEVIKEN
DRFILIQEYV DGMTLWDLLA TRPSARKKEA LFLQLLSVVA YAHGHGIMHR DIKPDNIMVR
FDGRLKLLDF GSAKKTTWKD HDTSPQGTLN FMPPEQFEGK TCLASDVWAL GIILYLFTIN
RLPLCQDNSV YPMDVEMEMT VVAPRDIIPH VPVHLEQVIM TCLSKDPAKR YRDGSILRND
LLGRLPDFGN GSQIPGW
//
