ID C0W2S0_9ACTO Unreviewed; 758 AA.
AC C0W2S0;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=HMPREF0058_0164 {ECO:0000313|EMBL:EEH67001.1};
OS Actinomyces urogenitalis DSM 15434.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=525246 {ECO:0000313|EMBL:EEH67001.1, ECO:0000313|Proteomes:UP000004778};
RN [1] {ECO:0000313|EMBL:EEH67001.1, ECO:0000313|Proteomes:UP000004778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15434 {ECO:0000313|EMBL:EEH67001.1,
RC ECO:0000313|Proteomes:UP000004778};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEH67001.1}.
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DR EMBL; ACFH01000008; EEH67001.1; -; Genomic_DNA.
DR RefSeq; WP_006549463.1; NZ_DS999576.1.
DR AlphaFoldDB; C0W2S0; -.
DR STRING; 103621.GCA_001067145_01194; -.
DR eggNOG; COG1200; Bacteria.
DR HOGENOM; CLU_005122_7_1_11; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000004778; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EEH67001.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000004778}.
FT DOMAIN 279..461
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 503..685
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 512..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 81249 MW; 545707A9DF7C8641 CRC64;
MDKLLGKRTA EQLGRQGVET AGDLLRLLPR RYDTWGDLTD LSSLVEGEQV TVQAQVMRSA
ARRARGGRPP ALMEALVTDG ASKMDVVFFG AAGLMAHYAE QFSPGTTVLL SGKVGIRHGH
RQLASPRFQV LDELDEAERA ELLARPMPIY PATESLPSWR VAKAVRTVLD QLTEQDVPEP
LPPEVRQAHD LVGALTAWRW VHTPEDAEQW RAARKRLRYE EAFVLQSALV QRRAAHEATH
AAVAWPRPGA GSLRASLDAS LPYTLTRGQE RVGRELEEAL ASTVPMQTLL QGDVGSGKTL
VALRAMLQVV GGGGQAALLA PTEVLAAQHR SSLEQLLGPL ARAGMLGGAS QATQVLLLTG
STPTPQRREI LARLAGGESA IVVGTHALLS DTVQIPFLGL VVVDEQHRFG VAQRDALRER
GNVRDPDTGQ LRTPHLLVMT ATPIPRTIAM TVFGDLDTAV LDELPAGRSP VATHLVPWER
TGWVEGIWQR AAREVAQGGR VYVVCPRIDA GEADPGDSAD DPQASASRGG TVPLFAAVPG
TGDEAADEES APARPLASVE DWVERLRGEP ALAGVSIGTL TGRMSQADKD AAMADFARGR
APVLVSTTVI EVGVDVPEAT MMVILDADRF GLSQLHQLRG RVGRGQRESL CVAVTGVEVG
SPAFHRLRAF AQTMDGFRLA EADLELRSEG NVLGAAQSGR RSDLDLLRVT RDGALIASAR
AEAEALVSAD PHLADHRDLA AAIADRLDEE SRAYLERA
//
