ID C0ZKK5_BREBN Unreviewed; 537 AA.
AC C0ZKK5;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN Name=nagA {ECO:0000313|EMBL:BAH45682.1};
GN Synonyms=yddD {ECO:0000313|EMBL:BAH45682.1};
GN OrderedLocusNames=BBR47_47050 {ECO:0000313|EMBL:BAH45682.1};
OS Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599).
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=358681 {ECO:0000313|EMBL:BAH45682.1, ECO:0000313|Proteomes:UP000001877};
RN [1] {ECO:0000313|EMBL:BAH45682.1, ECO:0000313|Proteomes:UP000001877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=47 / JCM 6285 / NBRC 100599
RC {ECO:0000313|Proteomes:UP000001877};
RA Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W.,
RA Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S.,
RA Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H.,
RA Udaka S., Tanikawa S., Fujita N.;
RT "Brevibacillus brevis strain 47, complete genome.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; AP008955; BAH45682.1; -; Genomic_DNA.
DR RefSeq; WP_015892943.1; NC_012491.1.
DR AlphaFoldDB; C0ZKK5; -.
DR STRING; 358681.BBR47_47050; -.
DR CAZy; GH3; Glycoside Hydrolase Family 3.
DR KEGG; bbe:BBR47_47050; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_008392_5_3_9; -.
DR Proteomes; UP000001877; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:BAH45682.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:BAH45682.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001877}.
FT DOMAIN 7..332
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 367..532
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 537 AA; 58724 MW; 70882937A56BAE58 CRC64;
MQAEHMTVEQ KVGQLLMIGY PTLDIPEEME VWIKQKQIGS VILFSRNIGT PEETYQRVQK
LQSWAYESWH PYPLLVGTDQ ENGVVSRLQK GATRFPGAMA LGATGNLDQA KRIYEATGEE
LRAAGISVNF APTVDVNNNP DNPVIGVRSF GEAPEQVARF GEAAIQGLLA SGVIPAIKHF
PGHGDTSIDS HEAVPVLGHD RTRLDQVELI PFQRSIAAGV PMVMVGHISL PSMDESGSPA
TYSKEIVTGI LRESLGFDGV AITDCMEMAA IAGTIGVAEA AVRSVQAGID LVLVSHTHEV
QQKTYDRLVA AIHSGELSEE RVNEAVNRVL QLKKRFLSWE QCLRAKGPSF DRVQHADMAK
SALAQAITLV KNQHQLLPLQ RSTQPLGVIF LGLANLTLAE DGQAASGDLV EPLRKYREVE
YYMMSTLNPT EDEGEMAAHV MSATEQIVVF TYNAHIFKGQ SLLVNRLIQQ GKKVVAVALR
NPYDLLVMPE VDAYLAVYDH TYQAIELVAN ILFGERKAAG HLPVSLFPSE KKQHGVG
//
