ID C0ZTB5_RHOE4 Unreviewed; 398 AA.
AC C0ZTB5;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Rieske-type oxygenase {ECO:0000256|ARBA:ARBA00030944};
GN Name=kshA {ECO:0000313|EMBL:BAH32088.1};
GN Synonyms=kshA1 {ECO:0000313|EMBL:BAH32088.1};
GN OrderedLocusNames=RER_13800 {ECO:0000313|EMBL:BAH32088.1};
OS Rhodococcus erythropolis (strain PR4 / NBRC 100887).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus; Rhodococcus erythropolis group.
OX NCBI_TaxID=234621 {ECO:0000313|EMBL:BAH32088.1, ECO:0000313|Proteomes:UP000002204};
RN [1] {ECO:0000313|Proteomes:UP000002204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RA Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT "Comparison of the complete genome sequences of Rhodococcus erythropolis
RT PR4 and Rhodococcus opacus B4.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAH32088.1, ECO:0000313|Proteomes:UP000002204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RX PubMed=16423019; DOI=10.1111/j.1462-2920.2005.00899.x;
RA Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N.,
RA Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K.,
RA Ito M., Narita H., Tago S., Fujita N., Harayama S.;
RT "Sequence analysis of three plasmids harboured in Rhodococcus erythropolis
RT strain PR4.";
RL Environ. Microbiol. 8:334-346(2006).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
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DR EMBL; AP008957; BAH32088.1; -; Genomic_DNA.
DR RefSeq; WP_020906621.1; NC_012490.1.
DR AlphaFoldDB; C0ZTB5; -.
DR SMR; C0ZTB5; -.
DR GeneID; 57488480; -.
DR KEGG; rer:RER_13800; -.
DR PATRIC; fig|234621.6.peg.1853; -.
DR eggNOG; COG4638; Bacteria.
DR HOGENOM; CLU_037178_1_0_11; -.
DR Proteomes; UP000002204; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProt.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:UniProt.
DR GO; GO:0008203; P:cholesterol metabolic process; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd03531; Rieske_RO_Alpha_KSH; 1.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR InterPro; IPR045605; KshA-like_C.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR PANTHER; PTHR21266:SF61; 3-KETOSTEROID-9-ALPHA-MONOOXYGENASE, OXYGENASE COMPONENT; 1.
DR PANTHER; PTHR21266; IRON-SULFUR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF19298; KshA_C; 1.
DR Pfam; PF00355; Rieske; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}.
FT DOMAIN 39..141
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 44523 MW; 9B792FFEDCA01C6F CRC64;
MALGTGPLTT TDASTQSGAG EEIREIEAAA PPARFARGWH CLGLSNTYRD GQPHQIEAFG
TSLVVFADSK GDIKILDAYC RHMGGNLAHG TVKGDSIACP FHDWRWGGNG KCTAIPYARR
VPPLAKTRAW TTLEKNGQLF VWHDPQGNPP PAEVTIPDIE GFGSDEWSDW SWNTLTIEGS
HCREIVDNVV DMAHFFYVHY SFPKYFKNIF EGHVASQYME SVGREDIISG TNYGDPNAVL
RSDASYFGPS YMIDWIKSEA NGQIIETVLI NCHYPISNNA FVLQYGAMVK KLPGMDDEST
AAMAAQFTEG VEMGFLQDVE IWKNKAPIDN PLLSEEDGPV YQLRRWYNQF YTDVENVTED
MTKRFEFEID TTRAVESWKR EVAENVAARD AQALETTS
//
