ID C1BYX2_ESOLU Unreviewed; 161 AA.
AC C1BYX2; A0A3P8XAN9;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=CKLF-like MARVEL transmembrane domain-containing protein 7 {ECO:0000313|EMBL:ACO14225.1};
GN Name=CKLF7 {ECO:0000313|EMBL:ACO14225.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|EMBL:ACO14225.1};
RN [1] {ECO:0000313|EMBL:ACO14225.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:ACO14225.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [2] {ECO:0000313|EMBL:ACO14225.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:ACO14225.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., Jantzen S., Cooper G., Davidson W.S., Koop B.F.;
RT "Esox lucius ESTs and full-length cDNAs.";
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSELUP00000001706.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [4] {ECO:0000313|Ensembl:ENSELUP00000001706.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BT079801; ACO14225.1; -; mRNA.
DR RefSeq; NP_001297930.1; NM_001311001.1.
DR STRING; 8010.ENSELUP00000001706; -.
DR Ensembl; ENSELUT00000016939.2; ENSELUP00000001706.2; ENSELUG00000026642.1.
DR GeneID; 105006532; -.
DR KEGG; els:105006532; -.
DR CTD; 112616; -.
DR GeneTree; ENSGT00510000048725; -.
DR OMA; LWTSYKV; -.
DR OrthoDB; 5315255at2759; -.
DR Proteomes; UP000265140; LG20.
DR Bgee; ENSELUG00000026642; Expressed in stomach and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008253; Marvel.
DR PANTHER; PTHR22776:SF89; CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7; 1.
DR PANTHER; PTHR22776; MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN; 1.
DR Pfam; PF01284; MARVEL; 1.
DR PROSITE; PS51225; MARVEL; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..152
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
SQ SEQUENCE 161 AA; 17850 MW; 118DA4602E02007F CRC64;
MSHTVVTTTT TTTSSSNVGY LNLGYTRSLQ GLLKIAQVVT LLIAFLCVYC SRRKWDYTAF
QYFEVVTLWF FIAFLIFYLM YVFRLQSKIA CINWTLTEFL HYAVGTVLVL IAAIVAAVKN
EGASELVAGS VFGFIATFLL AVSIWTSYKV TCGSQPTSAA V
//
