ID C1BZJ1_ESOLU Unreviewed; 133 AA.
AC C1BZJ1;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Cystatin-F {ECO:0000313|EMBL:ACO14444.1};
GN Name=CYTF {ECO:0000313|EMBL:ACO14444.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|EMBL:ACO14444.1};
RN [1] {ECO:0000313|EMBL:ACO14444.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:ACO14444.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [2] {ECO:0000313|EMBL:ACO14444.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:ACO14444.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., Jantzen S., Cooper G., Davidson W.S., Koop B.F.;
RT "Esox lucius ESTs and full-length cDNAs.";
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSELUP00000037584.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [4] {ECO:0000313|Ensembl:ENSELUP00000037584.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; BT080020; ACO14444.1; -; mRNA.
DR RefSeq; NP_001297968.1; NM_001311039.1.
DR MEROPS; I25.007; -.
DR Ensembl; ENSELUT00000027173.2; ENSELUP00000037584.1; ENSELUG00000017246.2.
DR GeneID; 105025514; -.
DR KEGG; els:105025514; -.
DR CTD; 8530; -.
DR GeneTree; ENSGT00940000160277; -.
DR OrthoDB; 4108209at2759; -.
DR Proteomes; UP000265140; LG06.
DR Bgee; ENSELUG00000017246; Expressed in mesonephros and 14 other cell types or tissues.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR InterPro; IPR042886; Cystatin-F.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR PANTHER; PTHR47141; CYSTATIN-F; 1.
DR PANTHER; PTHR47141:SF1; CYSTATIN-F; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 11..124
FT /note="Cystatin"
FT /evidence="ECO:0000259|SMART:SM00043"
SQ SEQUENCE 133 AA; 15136 MW; A9D49958D971B932 CRC64;
MFLVNCQRYT FIPGAPHEIS RNDSGVLKAA LHGTYSFNNK TNDAFLFKPS AIEKAERQIV
KGLNYIMEVD ISRTVCHKNG QNNTDLARCV FQPDGLLKQT FHCHFEVWTI PWLNFMKTID
LACSPSEKNI TSP
//
